Alessandro Sgambato
Overview
Explore the profile of Alessandro Sgambato including associated specialties, affiliations and a list of published articles.
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Articles
151
Citations
2586
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Recent Articles
1.
Lucchetti D, Rinaldi R, Artemi G, Salvia R, De Stefano F, Scieuzo C, et al.
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076518
Cancer is a leading cause of death worldwide, characterized by uncontrolled cell growth and multiple mutations. Chemotherapy is often associated with harmful side effects, and cancer cells may become resistant...
2.
Rinaldi R, Laurino S, Salvia R, Russi S, De Stefano F, Galasso R, et al.
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076512
Gastric cancer (GC) is one of the leading causes of cancer-related mortality worldwide, characterised by poor prognosis and limited responsiveness to chemotherapy. There is a need for new and more...
3.
Perelli L, Zhang L, Mangiameli S, Giannese F, Mahadevan K, Peng F, et al.
Nature
. 2025 Mar;
PMID: 40044861
Mesenchymal plasticity has been extensively described in advanced epithelial cancers; however, its functional role in malignant progression is controversial. The function of epithelial-to-mesenchymal transition (EMT) and cell plasticity in tumour...
4.
Tozzi M, Fiore A, Travaglione S, Marcon F, Rainaldi G, Germinario E, et al.
J Exp Clin Cancer Res
. 2025 Jan;
44(1):29.
PMID: 39876002
Background: Bacterial toxins are emerging as promising hallmarks of colorectal cancer (CRC) pathogenesis. In particular, Cytotoxic Necrotizing Factor 1 (CNF1) from E. coli deserves special consideration due to the significantly...
5.
Palazzo C, Mastrantonio R, Gioelli N, Testa E, Recco F, Lucchetti D, et al.
Cell Commun Signal
. 2025 Jan;
23(1):54.
PMID: 39875894
Background: Neuropilin-1 (NRP1) is a transmembrane protein involved in surface receptor complexes for a variety of extracellular signals. NRP1 expression in human cancers is associated with prominent angiogenesis and advanced...
6.
Albano F, Russi S, Laurino S, Mazzone P, Di Paola G, Zoppoli P, et al.
Front Cell Dev Biol
. 2024 Nov;
12:1481818.
PMID: 39563861
Introduction: Gastric cancer (GC) is an aggressive and heterogeneous malignancy marked by cellular and molecular diversity. In GC, cancer cells invade locally in the stomach at stage I and can...
7.
Tersigni C, Di Simone N, Lucchetti D, Colella F, Onori M, Perossini S, et al.
Reprod Sci
. 2024 Mar;
31(7):2043-2048.
PMID: 38453772
Placenta accreta spectrum (PAS) refers to excessive placental invasion into the maternal uterus and it is associated with high risk of obstetric haemorrhage and adverse maternal-neonatal outcomes. Currently, no specific...
8.
Agostini A, Guerriero I, Piro G, Quero G, Roberto L, Esposito A, et al.
J Transl Med
. 2023 Nov;
21(1):843.
PMID: 37996891
Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease. This is due to its aggressive course, late diagnosis and its intrinsic drugs resistance. The complexity of the tumor, in terms...
9.
Perelli L, Zhang L, Mangiameli S, Russell A, Giannese F, Peng F, et al.
bioRxiv
. 2023 Oct;
PMID: 37786705
Mesenchymal plasticity has been extensively described in advanced and metastatic epithelial cancers; however, its functional role in malignant progression, metastatic dissemination and therapy response is controversial. More importantly, the role...
10.
Lucchetti D, Colella F, Artemi G, Haque S, Sgambato A, Pellicano R, et al.
Crit Rev Oncol Hematol
. 2023 Sep;
191:104121.
PMID: 37690633
Extracellular vesicles (EVs) have gained tremendous interest in the search for next-generation therapeutics for the treatment of a range of pathologies, including cancer, especially due to their small size, biomolecular...