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Alessandro P Sparacio

Explore the profile of Alessandro P Sparacio including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Katz S, Barker T, Maul-Newby H, Sparacio A, Nguyen K, Maybrun C, et al.
PLoS Genet . 2022 Aug; 18(8):e1010348. PMID: 35960773
Epithelial cells secrete apical extracellular matrices to form protruding structures such as denticles, ridges, scales, or teeth. The mechanisms that shape these structures remain poorly understood. Here, we show how...
2.
Cohen J, Sparacio A, Belfi A, Forman-Rubinsky R, Hall D, Maul-Newby H, et al.
Elife . 2020 Sep; 9. PMID: 32975517
Biological tubes must develop and maintain their proper diameter to transport materials efficiently. These tubes are molded and protected in part by apical extracellular matrices (aECMs) that line their lumens....
3.
Sparacio A, Trojanowski N, Snetselaar K, Nelson M, Raizen D
PLoS One . 2020 May; 15(5):e0233059. PMID: 32433687
Complex extracellular structures exist throughout phylogeny, but the dynamics of their formation and dissolution are often opaque. One example is the pharyngeal grinder of the nematode Caenorhabditis elegans, an extracellular...