Alessandra Sottini
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Explore the profile of Alessandra Sottini including associated specialties, affiliations and a list of published articles.
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54
Citations
3693
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Recent Articles
11.
Carmona-Rivera C, Zhang Y, Dobbs K, Markowitz T, Dalgard C, Oler A, et al.
JCI Insight
. 2022 Jul;
7(16).
PMID: 35852866
Dysregulation in neutrophil extracellular trap (NET) formation and degradation may play a role in the pathogenesis and severity of COVID-19; however, its role in the pediatric manifestations of this disease,...
12.
Saettini F, Fazio G, Bonati M, Moratto D, Massa V, Di Fede E, et al.
Am J Med Genet A
. 2022 Mar;
188(7):2129-2134.
PMID: 35266289
The Rubinstein-Taybi syndrome (RSTS) is a rare developmental disorder characterized by craniofacial dysmorphisms, broad thumbs and toes, intellectual disability, growth deficiency, and recurrent infections. Mutations in the cyclic adenosine monophosphate...
13.
Carmona-Rivera C, Zhang Y, Dobbs K, Markowitz T, Dalgard C, Oler A, et al.
medRxiv
. 2022 Mar;
PMID: 35262093
Summary: NET formation and degradation are dysregulated in pediatric and symptomatic adult patients with various complications of COVID-19, in association with disease severity. NET degradation impairments are multifactorial and associated...
14.
Sacco K, Castagnoli R, Vakkilainen S, Liu C, Delmonte O, Oguz C, et al.
Nat Med
. 2022 Feb;
28(5):1050-1062.
PMID: 35177862
Pediatric Coronavirus Disease 2019 (pCOVID-19) is rarely severe; however, a minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might develop multisystem inflammatory syndrome in children (MIS-C),...
15.
Baronio M, Saettini F, Gazzurelli L, Rossi S, Marzollo A, Ricci S, et al.
J Clin Immunol
. 2021 Nov;
42(2):365-374.
PMID: 34802108
Purpose: Jacobsen syndrome (JS) is a rare form of genetic disorder that was recently classified as a syndromic immunodeficiency. Available detailed immunological data from JS patients are limited. Methods: Clinical...
16.
Quaresima V, Scarpazza C, Sottini A, Fiorini C, Signorini S, Delmonte O, et al.
Biol Sex Differ
. 2021 Aug;
12(1):48.
PMID: 34416920
No abstract available.
17.
Quaresima V, Scarpazza C, Sottini A, Fiorini C, Signorini S, Delmonte O, et al.
Biol Sex Differ
. 2021 Aug;
12(1):45.
PMID: 34380555
Background: Coronavirus disease 2019 (COVID-19) severity seems to be influenced by genetic background, sex, age, and presence of specific comorbidities. So far, little attention has been paid to sex-specific variations...
18.
Liu C, Martins A, Lau W, Rachmaninoff N, Chen J, Imberti L, et al.
Cell
. 2021 Mar;
184(7):1836-1857.e22.
PMID: 33713619
COVID-19 exhibits extensive patient-to-patient heterogeneity. To link immune response variation to disease severity and outcome over time, we longitudinally assessed circulating proteins as well as 188 surface protein markers, transcriptome,...
19.
Abers M, Delmonte O, Ricotta E, Fintzi J, Fink D, de Jesus A, et al.
JCI Insight
. 2020 Nov;
6(1).
PMID: 33232303
Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19). However, the utility of specific immune-based biomarkers to predict...
20.
Bastard P, Rosen L, Zhang Q, Michailidis E, Hoffmann H, Zhang Y, et al.
Science
. 2020 Sep;
370(6515).
PMID: 32972996
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease...