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Alessandra Marchetti

Explore the profile of Alessandra Marchetti including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 746
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Recent Articles
1.
Denti F, Guerra E, Caroppo F, Abruzzese P, Alessi F, Barone F, et al.
Healthcare (Basel) . 2024 Sep; 12(18). PMID: 39337146
This study, employing an interim analysis, investigates the effects of the Dermamecum protocol, a structured educational and tailored approach that stratifies ostomy patients into risk paths (green, yellow, red) based...
2.
Amicone L, Marchetti A, Cicchini C
J Exp Clin Cancer Res . 2023 Jun; 42(1):147. PMID: 37308974
The epithelial-to-mesenchymal transition (EMT) is a trans-differentiation process that endows epithelial cells with mesenchymal properties, including motility and invasion capacity; therefore, its aberrant reactivation in cancerous cells represents a critical...
3.
Ippolito F, Consalvi V, Noce V, Battistelli C, Cicchini C, Tripodi M, et al.
Cell Death Dis . 2023 Jan; 14(1):32. PMID: 36650140
YES-associated protein (YAP) is a transcriptional cofactor with a key role in the regulation of several physio-pathological cellular processes, by integrating multiple cell autonomous and microenvironmental cues. YAP is the...
4.
Bontempi G, Terri M, Garbo S, Montaldo C, Mariotti D, Bordoni V, et al.
Cell Death Dis . 2022 Nov; 13(11):965. PMID: 36396626
Histone acetylation/deacetylation play an essential role in modifying chromatin structure and in regulating cell plasticity in eukaryotic cells. Therefore, histone deacetylase (HDAC) pharmacological inhibitors are promising tools in the therapy...
5.
Amicone L, Marchetti A, Cicchini C
Cells . 2022 May; 11(10). PMID: 35626752
Epithelial-to-mesenchymal transition (EMT) is a dynamic program of cell plasticity aberrantly reactivated in cancer. The crosstalk between tumor cells and the tumoral microenvironment (TME) has a pivotal importance for the...
6.
Riccioni V, Trionfetti F, Montaldo C, Garbo S, Marocco F, Battistelli C, et al.
Int J Mol Sci . 2022 Jan; 23(2). PMID: 35055098
Heterogeneous nuclear ribonucleoproteins (hnRNPs) control gene expression by acting at multiple levels and are often deregulated in epithelial tumors; however, their roles in the fine regulation of cellular reprogramming, specifically...
7.
Noce V, Battistelli C, Cozzolino A, Consalvi V, Cicchini C, Strippoli R, et al.
Cell Death Dis . 2019 Oct; 10(10):768. PMID: 31601778
Yes-associated protein (YAP) is a transcriptional co-factor involved in many cell processes, including development, proliferation, stemness, differentiation, and tumorigenesis. It has been described as a sensor of mechanical and biochemical...
8.
Bisceglia F, Battistelli C, Noce V, Montaldo C, Zammataro A, Strippoli R, et al.
Front Pharmacol . 2019 Sep; 10:942. PMID: 31543815
The cytokine transforming growth factor β (TGFβ) plays a crucial role in the induction of both epithelial-to-mesenchymal transition (EMT) program and fibro-cirrhotic process in the liver, where it contributes also...
9.
Stazi G, Battistelli C, Piano V, Mazzone R, Marrocco B, Marchese S, et al.
Eur J Med Chem . 2018 Dec; 163:722-735. PMID: 30576903
In aggressive tumors, alkylglyceronephosphate synthase (AGPS) controls cellular ether phospholipid utilization and metabolism to promote cancer cell proliferation and motility. SAR studies on the first-in-class AGPS inhibitor 1, discovered by...
10.
Amicone L, Marchetti A
Transl Gastroenterol Hepatol . 2018 Jul; 3:24. PMID: 29971255
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on...