Alessandra Gonnelli
Overview
Explore the profile of Alessandra Gonnelli including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
169
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Recent Articles
1.
Sarogni P, Frusca V, Zamborlin A, Giannini N, Menicagli M, Brancato L, et al.
ACS Appl Mater Interfaces
. 2024 Aug;
16(33):43272-43282.
PMID: 39126693
Head and neck squamous cell carcinomas are characterized by a high incidence of recurrence, especially in patients with locally advanced disease. Standard treatment strategies can be associated with severe side...
2.
Gonnelli A, Gerbe de Thore M, Ermini M, Frusca V, Zamborlin A, Signolle N, et al.
Adv Mater
. 2024 May;
36(28):e2400949.
PMID: 38761135
Cisplatin chemoradiotherapy (CRT) is the established standard of care for managing locally advanced human papillomavirus-positive head/neck carcinoma. The typically young patients may suffer serious and long-time side effects caused by...
3.
Giannini N, Gadducci G, Fuentes T, Gonnelli A, Di Martino F, Puccini P, et al.
Front Oncol
. 2024 Apr;
14:1373453.
PMID: 38655137
FLASH-radiotherapy delivers a radiation beam a thousand times faster compared to conventional radiotherapy, reducing radiation damage in healthy tissues with an equivalent tumor response. Although not completely understood, this radiobiological...
4.
Sarogni P, Brindani N, Zamborlin A, Gonnelli A, Menicagli M, Mapanao A, et al.
Sci Rep
. 2024 Apr;
14(1):9150.
PMID: 38644364
Oral malignancies continue to have severe morbidity with less than 50% long-term survival despite the advancement in the available therapies. There is a persisting demand for new approaches to establish...
5.
Gonnelli A, Sarogni P, Giannini N, Linsalata S, Di Martino F, Zamborlin A, et al.
Artif Cells Nanomed Biotechnol
. 2024 Feb;
52(1):122-129.
PMID: 38315518
Locally advanced head and neck squamous cell carcinoma (LA-HNSCC) is characterized by high rate of recurrence, resulting in a poor survival. Standard treatments are associated with significant toxicities that impact...
6.
Crucitta S, Pasqualetti F, Gonnelli A, Ruglioni M, Luculli G, Cantarella M, et al.
BMC Cancer
. 2024 Jan;
24(1):31.
PMID: 38172718
Background: Circulating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor characteristics, biology and anatomic localization, cfDNA detection and analysis may be...
7.
Ursino S, Gadducci G, Giannini N, Gonnelli A, Fuentes T, Di Martino F, et al.
Front Oncol
. 2023 Nov;
13:1254601.
PMID: 37936603
Radiotherapy (RT) is performed in approximately 75% of patients with cancer, and its efficacy is often hampered by the low tolerance of the surrounding normal tissues. Recent advancements have demonstrated...
8.
Pasqualetti F, Miniati M, Gonnelli A, Gadducci G, Giannini N, Palagini L, et al.
Biology (Basel)
. 2023 Oct;
12(10).
PMID: 37887005
Despite countless papers in the field of radioresistance, researchers are still far from clearly understanding the mechanisms triggered in glioblastoma. Cancer stem cells (CSC) are important to the growth and...
9.
Gambacorta M, Chiloiro G, Masciocchi C, Mariani S, Romano A, Gonnelli A, et al.
Cancers (Basel)
. 2023 Jun;
15(12).
PMID: 37370819
LARC is managed by multimodal treatments whose intensity can be highly modulated. In this context, we need surrogate endpoints to help predict long-term outcomes and better personalize treatments. A previous...
10.
Hyperthermia Reduces Irradiation-Induced Tumor Repopulation in an In Vivo Pancreatic Carcinoma Model
Sarogni P, Zamborlin A, Mapanao A, Logghe T, Brancato L, van Zwol E, et al.
Adv Biol (Weinh)
. 2023 Mar;
7(10):e2200229.
PMID: 36861331
Pancreatic cancer has a poor prognosis due to its aggressive nature and ability to metastasize at an early stage. Currently, its management is still a challenge because this neoplasm is...