Alessandra Bosutti
Overview
Explore the profile of Alessandra Bosutti including associated specialties, affiliations and a list of published articles.
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38
Citations
514
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Recent Articles
1.
Eggelbusch M, Charlton B, Bosutti A, Ganse B, Giakoumaki I, Grootemaat A, et al.
Cell Rep Med
. 2024 Jan;
5(1):101372.
PMID: 38232697
Insulin sensitivity and metabolic flexibility decrease in response to bed rest, but the temporal and causal adaptations in human skeletal muscle metabolism are not fully defined. Here, we use an...
2.
Volpe P, Bosutti A, Nori A, Filadi R, Gherardi G, Trautmann G, et al.
J Gen Physiol
. 2022 Sep;
154(11).
PMID: 36149386
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are enriched at postsynaptic membrane compartments of the neuromuscular junction (NMJ), surrounding the subsynaptic nuclei and close to nicotinic acetylcholine receptors (nAChRs) of the motor endplate....
3.
Hendrickse P, Wust R, Ganse B, Giakoumaki I, Rittweger J, Bosutti A, et al.
J Cachexia Sarcopenia Muscle
. 2022 Sep;
13(6):2712-2723.
PMID: 36102002
Background: Muscle disuse from bed rest or spaceflight results in losses in muscle mass, strength and oxidative capacity. Capillary rarefaction may contribute to muscle atrophy and the reduction in oxidative...
4.
Bernareggi A, Bosutti A, Massaria G, Giniatullin R, Malm T, Sciancalepore M, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743058
Piezo1 channels are highly mechanically-activated cation channels that can sense and transduce the mechanical stimuli into physiological signals in different tissues including skeletal muscle. In this focused review, we summarize...
5.
Bosutti A, Dapas B, Grassi G, Bussani R, Zanconati F, Giudici F, et al.
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35456960
Although the eukaryotic elongation factor eEF1A1 plays a role in various tumours, there is little information on its prognosis/therapeutic value in prostate carcinoma. In high-grade and castration-resistant prostate carcinoma (CRPC),...
6.
Lorenzon P, Furlan S, Ravara B, Bosutti A, Massaria G, Bernareggi A, et al.
Metabolites
. 2021 Sep;
11(9).
PMID: 34564458
Homer represents a diversified family of scaffold and transduction proteins made up of several isoforms. Here, we present preliminary observations on skeletal muscle adaptation and plasticity in a transgenic model...
7.
Bosutti A, Giniatullin A, Odnoshivkina Y, Giudice L, Malm T, Sciancalepore M, et al.
Acta Physiol (Oxf)
. 2021 Jun;
233(4):e13702.
PMID: 34097801
Aim: Mechanosensitive Piezo1 ion channels emerged recently as important contributors to various vital functions including modulation of the blood supply to skeletal muscles. The specific Piezo1 channel agonist Yoda1 was...
8.
Ganse B, Bosutti A, Drey M, Degens H
Exp Cell Res
. 2021 Jan;
399(2):112463.
PMID: 33385417
Artificial gravity is a potential countermeasure to attenuate effects of weightlessness during long-term spaceflight, including losses of muscle mass and function, possibly to some extent attributable to disturbed neuromuscular interaction....
9.
Attias J, Grassi A, Bosutti A, Ganse B, Degens H, Drey M
Eur J Appl Physiol
. 2020 Aug;
120(11):2407-2415.
PMID: 32797257
Purpose: The objective of this study was to assess whether artificial gravity attenuates any long-duration head-down 6 bed rest (HDBR)-induced alterations in motor unit (MU) properties. Methods: Twenty-four healthy participants...
10.
Bosutti A, Mulder E, Zange J, Buhlmeier J, Ganse B, Degens H
Eur J Appl Physiol
. 2020 Mar;
120(5):969-983.
PMID: 32130485
Purpose: Space flight and bed rest (BR) lead to a rapid decline in exercise capacity. Whey protein plus potassium bicarbonate diet-supplementation (NUTR) could attenuate this effect by improving oxidative metabolism....