Alessandra Balduini
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Explore the profile of Alessandra Balduini including associated specialties, affiliations and a list of published articles.
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111
Citations
1803
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Recent Articles
1.
Lordier L, Di Buduo C, Kauskot A, Balayn N, Lavenu-Bombled C, Baschieri F, et al.
Haematologica
. 2025 Mar;
PMID: 40045897
Bernard Soulier Syndrome (BSS) is a severe bleeding disorder with moderate to severe thrombocytopenia, giant platelets, and platelet dysfunction, caused by biallelic mutations in GP1BA, GP1BB, or GP9 genes. We...
2.
Di Buduo C, Careddu F, Metti S, Lunghi M, Diprima S, Camilotto V, et al.
Blood Adv
. 2025 Feb;
PMID: 39951616
The pursuit of ex vivo erythrocyte generation has led to the development of various culture systems that simulate the bone marrow microenvironment. However, these models often fail to fully replicate...
3.
Ritter P, Oliveto S, Cordiglieri C, Fasciani A, Di Buduo C, Della Volpe L, et al.
Front Bioeng Biotechnol
. 2024 Oct;
12:1388312.
PMID: 39416278
Long-term culture of primary lymphocytes and hematopoietic stem and progenitor cells (HSPCs) is pivotal to their expansion and study. Furthermore, genetic engineering of the above-mentioned primary human cells has several...
4.
Capitanio D, Calledda F, Abbonante V, Cattaneo D, Moriggi M, Niccolo B, et al.
Leukemia
. 2024 Jul;
38(9):1971-1984.
PMID: 39025985
Despite increased understanding of the genomic landscape of Myeloproliferative Neoplasms (MPNs), the pathological mechanisms underlying abnormal megakaryocyte (Mk)-stromal crosstalk and fibrotic progression in MPNs remain unclear. We conducted mass spectrometry-based...
5.
Di Buduo C, Lunghi M, Kuzmenko V, Laurent P, Della Rosa G, Del Fante C, et al.
Adv Sci (Weinh)
. 2024 Mar;
11(18):e2308276.
PMID: 38514919
Hematopoietic stem and progenitor cells (HSPCs) continuously generate platelets throughout one's life. Inherited Platelet Disorders affect ≈ 3 million individuals worldwide and are characterized by defects in platelet formation or...
6.
7.
Abbonante V, Karkempetzaki A, Leon C, Krishnan A, Huang N, Di Buduo C, et al.
Am J Hematol
. 2024 Jan;
99(3):336-349.
PMID: 38165047
Mechanisms through which mature megakaryocytes (Mks) and their progenitors sense the bone marrow extracellular matrix to promote lineage differentiation in health and disease are still partially understood. We found PIEZO1,...
8.
Della Rosa G, Di Buduo C, Balduini A
J Thromb Haemost
. 2023 Oct;
21(11):3078-3081.
PMID: 37858524
No abstract available.
9.
Calledda F, Malara A, Balduini A
Curr Opin Hematol
. 2023 Aug;
30(6):237-244.
PMID: 37548363
Purpose Of Review: Myelofibrosis (MF) is primarily driven by constitutive activation of the Janus kinase/signal transducer of activators of transcription (JAK/STAT) pathway. While JAK inhibitors have shown to alleviate disease...
10.
Di Buduo C, Miguel C, Balduini A
Res Pract Thromb Haemost
. 2023 Jul;
7(4):100197.
PMID: 37416054
A State of the Art lecture titled "Megakaryocytes and different thrombopoietic environments" was presented at the ISTH Congress in 2022. Circulating platelets are specialized cells produced by megakaryocytes. Leading studies...