Alessandra Balduini
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Explore the profile of Alessandra Balduini including associated specialties, affiliations and a list of published articles.
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111
Citations
1803
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Recent Articles
11.
Astigiano C, Piacente F, Laugieri M, Benzi A, Di Buduo C, Miguel C, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047732
Sirtuin 6 (SIRT6) is a member of the mammalian NAD-dependent deac(et)ylase sirtuin family. SIRT6's anti-inflammatory roles are emerging increasingly often in different diseases and cell types, including endothelial cells. In...
12.
Lecca M, Pehlivan D, Suner D, Weiss K, Coste T, Zweier M, et al.
Am J Hum Genet
. 2023 Mar;
110(4):681-690.
PMID: 36996813
The blood-brain barrier (BBB) is an essential gatekeeper for the central nervous system and incidence of neurodevelopmental disorders (NDDs) is higher in infants with a history of intracerebral hemorrhage (ICH)....
13.
Antonelli A, Scarpa E, Bruzzone S, Astigiano C, Piacente F, Bruschi M, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982232
Sinusoidal endothelial cells are the predominant vascular surface of the bone marrow and constitute the functional hematopoietic niche where hematopoietic stem and progenitor cells receive cues for self-renewal, survival, and...
14.
Marin-Quilez A, Diaz-Ajenjo L, Di Buduo C, Zamora-Canovas A, Lozano M, Benito R, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982178
Protein glycosylation, including sialylation, involves complex and frequent post-translational modifications, which play a critical role in different biological processes. The conjugation of carbohydrate residues to specific molecules and receptors is...
15.
Marin-Quilez A, Di Buduo C, Benito R, Balduini A, Rivera J, Bastida J
Platelets
. 2023 Feb;
34(1):2176699.
PMID: 36846897
gene encodes the uridine diphosphate [UDP]-galactose-4-epimerase, which catalyzes the bidirectional interconversion of UDP-glucose to UDP-galactose, and UDP-N-acetyl-glucosamine to UDP-N-acetyl-galactosamine. In that way, GALE balances, through reversible epimerization, the pool of...
16.
Basso-Valentina F, Donada A, Manchev V, Lisetto M, Balayn N, Martin J, et al.
Haematologica
. 2023 Feb;
108(8):2130-2145.
PMID: 36794499
Sustained ANKRD26 expression associated with germline ANKRD26 mutations causes thrombocytopenia 2 (THC2), an inherited platelet disorder associated with a predisposition to leukemia. Some patients also present with erythrocytosis and/or leukocytosis....
17.
Simeone P, Liani R, Tripaldi R, Ciotti S, Recchiuti A, Abbonante V, et al.
Haematologica
. 2022 Dec;
108(4):1141-1157.
PMID: 36546455
Cardiovascular (CV) disease prevention with low-dose aspirin can be less effective in patients with a faster recovery of platelet (PLT) cyclooxygenase (COX)-1 activity during the 24-hour dosing interval. We previously...
18.
Migliaccio A, Balduini A, Zhan H
Front Oncol
. 2022 Dec;
12:1090658.
PMID: 36505825
No abstract available.
19.
Marin-Quilez A, Di Buduo C, Diaz-Ajenjo L, Abbonante V, Vuelta E, Soprano P, et al.
Blood
. 2022 Nov;
141(4):406-421.
PMID: 36395340
Glycosylation is recognized as a key process for proper megakaryopoiesis and platelet formation. The enzyme uridine diphosphate (UDP)-galactose-4-epimerase, encoded by GALE, is involved in galactose metabolism and protein glycosylation. Here,...
20.
Malara A, Gruppi C, Massa M, Tira M, Rosti V, Balduini A, et al.
Front Oncol
. 2022 Oct;
12:987643.
PMID: 36212480
In primary myelofibrosis, extra-domain A fibronectin (EDA-FN), the result of alternative splicing of FN gene, sustains megakaryocyte proliferation and confers a pro-inflammatory phenotype to bone marrow cell niches. In this...