Alena Stancakova
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Explore the profile of Alena Stancakova including associated specialties, affiliations and a list of published articles.
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111
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18995
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Recent Articles
1.
Willems S, Ng N, Fernandez J, Fine R, Wheeler E, Wessel J, et al.
Wellcome Open Res
. 2024 Sep;
8():483.
PMID: 39280063
Background: Genome-wide association studies for glycemic traits have identified hundreds of loci associated with these biomarkers of glucose homeostasis. Despite this success, the challenge remains to link variant associations to...
2.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature
. 2024 Feb;
627(8003):347-357.
PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...
3.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
medRxiv
. 2023 Apr;
PMID: 37034649
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes. To characterise the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study...
4.
Mahajan A, Spracklen C, Zhang W, Ng M, Petty L, Kitajima H, et al.
Nat Genet
. 2022 May;
54(5):560-572.
PMID: 35551307
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the Diabetes Meta-Analysis...
5.
Ezzat S, Zheng L, Florez J, Stefan N, Mayr T, Hliang M, et al.
Cell Metab
. 2020 Oct;
32(4):691.
PMID: 33027678
No abstract available.
6.
Clark D, Okada Y, Moore K, Mason D, Pirastu N, Gandin I, et al.
Nat Commun
. 2019 Nov;
10(1):4957.
PMID: 31673082
In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because...
7.
Evangelou E, Gao H, Chu C, Ntritsos G, Blakeley P, Butts A, et al.
Nat Hum Behav
. 2019 Jul;
3(9):950-961.
PMID: 31358974
Excessive alcohol consumption is one of the main causes of death and disability worldwide. Alcohol consumption is a heritable complex trait. Here we conducted a meta-analysis of genome-wide association studies...
8.
Sung Y, de las Fuentes L, Winkler T, Chasman D, Bentley A, Kraja A, et al.
Hum Mol Genet
. 2019 May;
28(15):2615-2633.
PMID: 31127295
Elevated blood pressure (BP), a leading cause of global morbidity and mortality, is influenced by both genetic and lifestyle factors. Cigarette smoking is one such lifestyle factor. Across five ancestries,...
9.
Bentley A, Sung Y, Brown M, Winkler T, Kraja A, Ntalla I, et al.
Nat Genet
. 2019 Mar;
51(4):636-648.
PMID: 30926973
The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a...
10.
Vangipurapu J, Stancakova A, Smith U, Kuusisto J, Laakso M
Diabetes
. 2019 Mar;
68(6):1353-1358.
PMID: 30885989
Several amino acids (AAs) have been shown to be associated with insulin resistance and increased risk of type 2 diabetes, but no previous studies have investigated the association of AAs...