Aleksandra Romaniuk-Drapala
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Explore the profile of Aleksandra Romaniuk-Drapala including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
78
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Recent Articles
1.
Romaniuk-Drapala A, Kosicka-Noworzyn K, Sheng Y, Yohn C, Brunetti L, Kagan L
Sci Rep
. 2025 Feb;
15(1):5347.
PMID: 39948154
Given the obesity epidemic and the prevalence of comorbidities, there is an ongoing need to understand the health consequences of this disease state better. Understanding gene expression signals will facilitate...
2.
Kosicka-Noworzyn K, Romaniuk-Drapala A, Sheng Y, Yohn C, Brunetti L, Kagan L
Pharmacol Rep
. 2024 Oct;
76(6):1429-1442.
PMID: 39412582
Background: Pathophysiological changes associated with obesity might impact various drug pharmacokinetics (PK) parameters. The liver and kidneys are the primary organs involved in drug clearance, and the function of hepatic...
3.
Romaniuk-Drapala A, Skupin-Mrugalska P, Garbuzenko O, Hatefi A, Minko T
Cancer Cell Int
. 2024 Aug;
24(1):285.
PMID: 39135053
Background: Olaparib is a PARP inhibitor inducing synthetic lethality in tumors with deficient homologous recombination (HRD) caused by BRCA1/2 mutations. The FDA has approved monotherapy for first-line platinum-sensitive, recurrent high-grade...
4.
Romaniuk-Drapala A, Toton E, Taube M, Idzik M, Rubis B, Lisiak N
Cancers (Basel)
. 2024 Jul;
16(13).
PMID: 39001543
Breast cancer is one of the most frequently detected malignancies worldwide. It is responsible for more than 15% of all death cases caused by cancer in women. Breast cancer is...
5.
Toton E, Lisiak N, Romaniuk-Drapala A, Framski G, Wyszko E, Ostrowski T
Bioorg Med Chem Lett
. 2024 Jan;
100:129628.
PMID: 38280656
N-[(Furan-2-yl)methyl]adenosine (kinetin riboside) and its seven synthesized analogues were examined for the ability to inhibit the growth of five human carcinoma cell lines and for comparison of normal human lung...
6.
Budzianowska A, Toton E, Romaniuk-Drapala A, Kikowska M, Budzianowski J
Life (Basel)
. 2023 Feb;
13(2).
PMID: 36836912
The aim of the study is to investigate whether the bioactive compounds isolated from inflorescences, namely, phenylethanoid glucosides, acteoside, plantamajoside, and a flavonoid, isorhamnetin-3--rutinoside-4'--glucoside, possessed cytotoxic activity against the selected...
7.
Romaniuk-Drapala A, Toton E, Konieczna N, Machnik M, Barczak W, Kowal D, et al.
Cells
. 2021 Apr;
10(4).
PMID: 33920284
Telomerase is known to contribute to telomere maintenance and to provide cancer cell immortality. However, numerous reports are showing that the function of the enzyme goes far beyond chromosome ends....
8.
Romaniuk-Drapala A, Lisiak N, Toton E, Matysiak A, Nawrot J, Nowak G, et al.
Chem Biol Interact
. 2021 Apr;
342:109479.
PMID: 33878320
The present study was designed to identify the biological activity of three ecdysones, i.e., 20-hydroxyecdysone (20-HE), ajugasterone C, and polypodine B isolated from Serratula coronata. The main objective was to...
9.
Holysz H, Paszel-Jaworska A, Romaniuk-Drapala A, Grodecka-Gazdecka S, Rubis B
Mol Biol Rep
. 2021 Apr;
48(4):3237-3244.
PMID: 33864589
On a global scale, breast cancer is the most common type of cancer in women, and it is still a growing problem. Therefore, new prognostic or diagnostic markers are required...
10.
Dobrucka R, Romaniuk-Drapala A, Kaczmarek M
Biomed Microdevices
. 2021 Mar;
23(1):14.
PMID: 33683457
Metal combinations have been attracting the attention of scientists for some time. They usually exhibit new characteristics that are different from the ones possessed by their components. In this work,...