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Aleksandra Paterek

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Articles 26
Citations 113
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Recent Articles
1.
Nogajski L, Mazuruk M, Kacperska M, Kurpias M, Maczewski M, Nowakowski M, et al.
Cardiovasc Diabetol . 2024 Oct; 23(1):389. PMID: 39472958
Epicardial adipose tissue (EAT) is a unique fat depot located between the myocardium and the visceral layer of pericardium. It can be further subdivided into pericoronary (PCAT), periatrial (PAAT) and...
2.
Paterek A, Zaleska-Kociecka M, Wojdynska Z, Kalisz M, Litwiniuk A, Leszek P, et al.
Obes Rev . 2024 Aug; 25(12):e13820. PMID: 39187402
Epicardial adipose tissue (EAT) is a fat depot covering the heart. No physical barrier separates EAT from the myocardium, so EAT can easily affect the underlying cardiac muscle. EAT can...
3.
Okninska M, Paterek A, Grzanka M, Zajda K, Surzykiewicz M, Rolski F, et al.
Br J Pharmacol . 2024 Jul; 181(20):4050-4066. PMID: 38952183
Background And Purpose: Pulmonary hypertension (PH) results from pulmonary vasculopathy, initially leading to a compensatory right ventricular (RV) hypertrophy, and eventually to RV failure. Hypoxia can trigger both pulmonary vasculopathy...
4.
Paterek A, Zaleska-Kociecka M, Surzykiewicz M, Wojdynska Z, Leszek P, Maczewski M
Eur Heart J Cardiovasc Pharmacother . 2024 Apr; 10(4):353-360. PMID: 38641424
Non-coding RNA (ncRNA) therapeutics can target either ncRNAs or conventional messenger RNA, offering both superior pharmacokinetics and selectivity to conventional therapies and addressing new, previously unexplored pathways. Although no ncRNA...
5.
Okninska M, Duda M, Czarnowska E, Bierla J, Paterek A, Maczewski M, et al.
Sci Rep . 2024 Feb; 14(1):3460. PMID: 38342936
The incidence of life-threatening ventricular arrhythmias, the most common cause of sudden cardiac death (SCD), depends largely on the arrhythmic substrate that develops in the myocardium during the aging process....
6.
Delaunay M, Paterek A, Gautschi I, Scherler G, Diviani D
Biochim Biophys Acta Mol Cell Res . 2024 Jan; 1871(3):119674. PMID: 38242328
Cardiac fibrosis is a major cause of dysfunctions and arrhythmias in failing hearts. At the cellular level fibrosis is mediated by cardiac myofibroblasts, which display an increased migratory capacity and...
7.
Zaleska-Kociecka M, Wojdynska Z, Kalisz M, Litwiniuk A, Maczewski M, Leszek P, et al.
Heart Rhythm . 2023 Nov; 21(2):206-212. PMID: 37972673
The arrhythmogenic role of epicardial adipose tissue (EAT) in atrial arrhythmias is well established, but its effect on ventricular arrhythmias has been significantly less investigated. Since ventricular arrhythmias are thought...
8.
Okninska M, Zajda K, Zambrowska Z, Grzanka M, Paterek A, Mackiewicz U, et al.
JACC Heart Fail . 2023 May; 12(2):235-247. PMID: 37140511
Right ventricular (RV) function and eventually failure determine outcome in patients with pulmonary arterial hypertension (PAH). Initially, RV responds to an increased load caused by PAH with adaptive hypertrophy; however,...
9.
Paterek A, Okninska M, Pilch Z, Sosnowska A, Ramji K, Mackiewicz U, et al.
Cancers (Basel) . 2023 Apr; 15(7). PMID: 37046852
Background: Multiple myeloma (MM) is associated with increased cardiovascular morbidity and mortality, while MM therapies also result in adverse cardiac effects. Endothelial dysfunction and impaired nitric oxide (NO) pathway is...
10.
Paterek A, Okninska M, Maczewski M, Mackiewicz U
Biomolecules . 2022 Nov; 12(11). PMID: 36421728
Right ventricular dysfunction (RVD) can follow primary pulmonary diseases, but the most common cause of its development is left-sided heart failure (HF). RVD is associated with HF progression, increased risk...