Alejandro Llorente
Overview
Explore the profile of Alejandro Llorente including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
105
Followers
0
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Recent Articles
1.
Duch P, Diaz-Valdivia N, Gabasa M, Ikemori R, Arshakyan M, Fernandez-Nogueira P, et al.
Cancer Sci
. 2024 Mar;
115(5):1505-1519.
PMID: 38476010
The fibrotic tumor microenvironment is a pivotal therapeutic target. Nintedanib, a clinically approved multikinase antifibrotic inhibitor, is effective against lung adenocarcinoma (ADC) but not squamous cell carcinoma (SCC). Previous studies...
2.
Juste-Lanas Y, Diaz-Valdivia N, Llorente A, Ikemori R, Bernardo A, Arshakyan M, et al.
Br J Cancer
. 2022 Dec;
128(6):967-981.
PMID: 36572730
Background: The TGF-β1 transcription factor SMAD3 is epigenetically repressed in tumour-associated fibroblasts (TAFs) from lung squamous cell carcinoma (SCC) but not adenocarcinoma (ADC) patients, which elicits a compensatory increase in...
3.
Alcaraz J, Ikemori R, Llorente A, Diaz-Valdivia N, Reguart N, Vizoso M
Cancers (Basel)
. 2021 Aug;
13(15).
PMID: 34359678
Lung cancer is the leading cause of cancer-related death worldwide. The desmoplastic stroma of lung cancer and other solid tumors is rich in tumor-associated fibroblasts (TAFs) exhibiting an activated/myofibroblast-like phenotype....
4.
Gabasa M, Radisky E, Ikemori R, Bertolini G, Arshakyan M, Hockla A, et al.
Cancer Lett
. 2021 Mar;
507:1-12.
PMID: 33684534
Large cell carcinoma (LCC) is a rare and aggressive lung cancer subtype with poor prognosis and no targeted therapies. Tumor-associated fibroblasts (TAFs) derived from LCC tumors exhibit premature senescence, and...
5.
Gabasa M, Arshakyan M, Llorente A, Chulia-Peris L, Pavelescu I, Xaubet A, et al.
Int J Mol Sci
. 2020 Nov;
21(22).
PMID: 33182538
Pro-inflammatory cytokines like interleukin-1β (IL-1β) are upregulated during early responses to tissue damage and are expected to transiently compromise the mechanical microenvironment. Fibroblasts are key regulators of tissue mechanics in...
6.
Llorente A, Garcia-Herranz M, Cebrian M, Moro E
PLoS One
. 2015 May;
10(5):e0128692.
PMID: 26020628
Recent widespread adoption of electronic and pervasive technologies has enabled the study of human behavior at an unprecedented level, uncovering universal patterns underlying human activity, mobility, and interpersonal communication. In...
7.
Krumme C, Llorente A, Cebrian M, Pentland A, Moro E
Sci Rep
. 2013 Apr;
3:1645.
PMID: 23598917
We consider hundreds of thousands of individual economic transactions to ask: how predictable are consumers in their merchant visitation patterns? Our results suggest that, in the long-run, much of our...
8.
Guimera R, Llorente A, Moro E, Sales-Pardo M
PLoS One
. 2012 Sep;
7(9):e44620.
PMID: 22984533
With ever-increasing available data, predicting individuals' preferences and helping them locate the most relevant information has become a pressing need. Understanding and predicting preferences is also important from a fundamental...