Alejandro Akrouh
Overview
Explore the profile of Alejandro Akrouh including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
331
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Recent Articles
1.
Perez-Ortega J, Akrouh A, Yuste R
Nat Commun
. 2024 Apr;
15(1):3192.
PMID: 38609354
Neuronal ensembles are groups of neurons with correlated activity associated with sensory, motor, and behavioral functions. To explore how ensembles encode information, we investigated responses of visual cortical neurons in...
2.
ONeil D, Akrouh A, Yuste R
STAR Protoc
. 2023 Sep;
4(3):102543.
PMID: 37659084
Neuronal ensembles are coordinated groups of neurons that serve as functional building blocks of neural circuits. Here, we present PatMap, a computational toolbox for identifying pattern-completion neurons, key trigger cells...
3.
Carrillo-Reid L, Han S, Yang W, Akrouh A, Yuste R
Cell
. 2019 Jul;
178(2):447-457.e5.
PMID: 31257030
Neurons in cortical circuits are often coactivated as ensembles, yet it is unclear whether ensembles play a functional role in behavior. Some ensemble neurons have pattern completion properties, triggering the...
4.
Akrouh A, Kerschensteiner D
J Neurophysiol
. 2015 Aug;
114(4):2431-8.
PMID: 26311183
Amacrine cells (ACs) are the most diverse class of neurons in the retina. The variety of signals provided by ACs allows the retina to encode a wide range of visual...
5.
Akrouh A, Kerschensteiner D
Neuron
. 2013 Jul;
79(2):322-34.
PMID: 23830830
The developing retina generates spontaneous glutamatergic (stage III) waves of activity that sequentially recruit neighboring ganglion cells with opposite light responses (ON and OFF RGCs). This activity pattern is thought...
6.
Kurata H, Akrouh A, Li J, Marton L, Nichols C
J Biol Chem
. 2013 Jan;
288(9):6591-601.
PMID: 23300089
Steeply voltage-dependent inward rectification of Kir (inwardly rectifying potassium) channels arises from blockade by cytoplasmic polyamines. These polycationic blockers traverse a long (>70 Å) pore, displacing multiple permeant ions, en...
7.
Lin Y, Akrouh A, Hsu Y, Hughes N, Nichols C, De Leon D
Channels (Austin)
. 2012 May;
6(2):133-8.
PMID: 22562119
KATP channels regulate insulin secretion by coupling β-cell metabolism to membrane excitability. These channels are comprised of a pore-forming Kir6.2 tetramer which is enveloped by four regulatory SUR1 subunits. ATP...
8.
Zhang H, Akrouh A, Kurata H, Remedi M, Lawton J, Nichols C
J Mol Cell Cardiol
. 2010 Dec;
50(3):552-60.
PMID: 21185839
Murine ventricular and atrial ATP-sensitive potassium (K(ATP)) channels contain different sulfonylurea receptors (ventricular K(ATP) channels are Kir6.2/SUR2A complexes, while atrial K(ATP) channels are Kir6.2/SUR1 complexes). HMR 1098, the sodium salt...
9.
Rojas P, Akrouh A, Eisenman L, Mennerick S
J Neurophysiol
. 2010 Nov;
105(1):366-79.
PMID: 21068264
GABA(A) receptors are found on the somatodendritic compartment and on the axon initial segment of many principal neurons. The function of axonal receptors remains obscure, although it is widely assumed...
10.
Loechner K, Akrouh A, Kurata H, Dionisi-Vici C, Maiorana A, Pizzoferro M, et al.
Diabetes
. 2010 Oct;
60(1):209-17.
PMID: 20980454
Objective: The ATP-sensitive K(+) channel (K(ATP)) controls insulin secretion from the islet. Gain- or loss-of-function mutations in channel subunits underlie human neonatal diabetes and congenital hyperinsulinism (HI), respectively. In this...