Alejandra Lopez-Juarez
Overview
Explore the profile of Alejandra Lopez-Juarez including associated specialties, affiliations and a list of published articles.
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13
Citations
199
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Recent Articles
1.
Eguibar J, Cortes C, Hernandez V, Lopez-Juarez A, Piazza V, Carmona D, et al.
PLoS One
. 2024 Mar;
19(3):e0298208.
PMID: 38427650
The taiep rat is a tubulin mutant with an early hypomyelination followed by progressive demyelination of the central nervous system due to a point mutation in the Tubb4a gene. It...
2.
Rastoldo G, Watabe I, Lapotre A, Tonetto A, Lopez-Juarez A, Tighilet B
Cells
. 2022 Nov;
11(22).
PMID: 36429025
We previously reported adult reactive neurogliogenesis in the deafferented vestibular nuclei following unilateral vestibular neurectomy (UVN) in the feline and the rodent model. Recently, we demonstrated that UVN induced a...
3.
Rastoldo G, Marouane E, El-Mahmoudi N, Pericat D, Watabe I, Lapotre A, et al.
Cells
. 2022 Feb;
11(4).
PMID: 35203333
Unilateral vestibular lesions induce a vestibular syndrome, which recovers over time due to vestibular compensation. The therapeutic effect of L-Thyroxine (L-T4) on vestibular compensation was investigated by behavioral testing and...
4.
Alata M, Gonzalez-Vega A, Piazza V, Kleinert-Altamirano A, Cortes C, Ahumada-Juarez J, et al.
Front Neurol
. 2021 Aug;
12:702039.
PMID: 34335454
Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) is a central neurodegenerative disease due to mutations in the tubulin beta-4A (TUBB4A) gene, characterized by motor development delay, abnormal...
5.
Rastoldo G, El Mahmoudi N, Marouane E, Pericat D, Watabe I, Toneto A, et al.
Prog Neurobiol
. 2020 Aug;
196:101899.
PMID: 32858093
We previously revealed adult reactive neurogenesis in deafferented vestibular nuclei following unilateral vestibular neurectomy (UVN) in the feline model. We recently replicated the same surgery in a rodent model and...
6.
Lopez-Juarez A, Gonzalez-Vega A, Kleinert-Altamirano A, Piazza V, Garduno-Robles A, Alata M, et al.
J Comp Neurol
. 2020 Jul;
529(5):957-968.
PMID: 32681585
Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) is a neurodegenerative disease due to mutations in TUBB4A. Patients suffer from extrapyramidal movements, spasticity, ataxia, and cognitive deficits. Magnetic...
7.
Lopez-Juarez A, Lahlou H, Ripoll C, Cazals Y, Brezun J, Wang Q, et al.
Mol Ther
. 2019 Apr;
27(6):1101-1113.
PMID: 31005598
Most cases of sensorineural deafness are caused by degeneration of hair cells. Although stem/progenitor cell therapy is becoming a promising treatment strategy in a variety of organ systems, cell engraftment...
8.
Lahlou H, Nivet E, Lopez-Juarez A, Fontbonne A, Assou S, Zine A
Front Mol Neurosci
. 2019 Jan;
11:452.
PMID: 30618604
Age-related neurosensory deficit of the inner ear is mostly due to a loss of hair cells (HCs). Development of stem cell-based therapy requires a better understanding of factors and signals...
9.
Lahlou H, Lopez-Juarez A, Fontbonne A, Nivet E, Zine A
PLoS One
. 2018 Jun;
13(6):e0198954.
PMID: 29902227
The inner ear represents a promising system to develop cell-based therapies from human induced pluripotent stem cells (hiPSCs). In the developing ear, Notch signaling plays multiple roles in otic region...
10.
Pourabdolhossein F, Mozafari S, Morvan-Dubois G, Mirnajafi-Zadeh J, Lopez-Juarez A, Pierre-Simons J, et al.
PLoS One
. 2014 Sep;
9(9):e106378.
PMID: 25184636
Background: Inhibitory factors have been implicated in the failure of remyelination in demyelinating diseases. Myelin associated inhibitors act through a common receptor called Nogo receptor (NgR) that plays critical inhibitory...