Aleisha M Moore
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Explore the profile of Aleisha M Moore including associated specialties, affiliations and a list of published articles.
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20
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446
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Recent Articles
1.
Dillon K, Lohr D, Novak A, Petriv A, Neifert N, Moore A
Endocrinology
. 2024 Sep;
165(10).
PMID: 39253941
Reproductive function in mammals depends on the ability of progesterone (P4) to suppress pulsatile gonadotrophin-releasing hormone (GnRH) and luteinizing hormone (LH) secretion in a homeostatic-negative feedback loop. Previous research identified...
2.
Moore A
Elife
. 2024 Apr;
13.
PMID: 38591514
Prolactin suppresses the ovarian cycles of lactating mice by directly repressing the activity of a cell population known as kisspeptin neurons.
3.
Moore A, Novak A, Lehman M
Endocrinology
. 2024 Jan;
165(2).
PMID: 38170643
There is considerable evidence that synchronized activity within a reciprocally connected population of cells in the arcuate nucleus (ARC) coexpressing kisspeptin, neurokinin B (NKB), and dynorphin (KNDy cells) is crucial...
4.
Goodman R, Moore A, Onslow K, Hileman S, Hardy S, Bowdridge E, et al.
Endocrinology
. 2023 Sep;
164(11).
PMID: 37776515
The current model for the synchronization of GnRH neural activity driving GnRH and LH pulses proposes that a set of arcuate (ARC) neurons that contain kisspeptin, neurokinin B, and dynorphin...
5.
6.
Jamieson B, Moore A, Lohr D, Thomas S, Coolen L, Lehman M, et al.
Front Endocrinol (Lausanne)
. 2022 Aug;
13:951344.
PMID: 35992143
Polycystic ovary syndrome (PCOS) is associated with elevated androgen and luteinizing hormone (LH) secretion and with oligo/anovulation. Evidence indicates that elevated androgens impair sex steroid hormone feedback regulation of pulsatile...
7.
Moore A
Clin Endocrinol (Oxf)
. 2022 Mar;
97(2):199-207.
PMID: 35349177
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy and cause of infertility in women of reproductive age worldwide. Despite diagnostic features of anovulation, polycystic ovarian morphology, and high androgen...
8.
Moore A, Coolen L, Lehman M
Proc Natl Acad Sci U S A
. 2022 Feb;
119(6).
PMID: 35110409
A hypothalamic pulse generator located in the arcuate nucleus controls episodic release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) and is essential for reproduction. Recent evidence suggests this generator...
9.
Moore A, Lohr D, Coolen L, Lehman M
Endocrinology
. 2021 Aug;
162(11).
PMID: 34346492
Polycystic ovarian syndrome (PCOS), the most common endocrinopathy affecting women worldwide, is characterized by elevated luteinizing hormone (LH) pulse frequency due to the impaired suppression of gonadotrophin-releasing hormone (GnRH) release...
10.
Moore A, Coolen L, Lehman M
Sci Rep
. 2019 Oct;
9(1):14768.
PMID: 31611573
Neurons in the hypothalamic arcuate nucleus (ARC) that co-express kisspeptin, neurokinin B and dynorphin (KNDy cells) are essential for mammalian reproduction as key regulators of gonadotropin-releasing hormone (GnRH) secretion. Although...