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Aleisha M Moore

Explore the profile of Aleisha M Moore including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
11.
Porter D, Moore A, Cobern J, Padmanabhan V, Goodman R, Coolen L, et al.
Endocrinology . 2019 Aug; 160(11):2529-2542. PMID: 31415088
Prenatal testosterone (T)-treated female sheep display reproductive deficits similar to women with polycystic ovarian syndrome (PCOS), including an increase in LH pulse frequency due to actions of the central GnRH...
12.
Moore A, Abbott G, Mair J, Prescott M, Campbell R
J Neuroendocrinol . 2018 Nov; 30(12):e12657. PMID: 30415474
Gonadotrophin-releasing hormone (GnRH) neurone function is dependent upon gonadal steroid hormone feedback, which is communicated in large part through an afferent neuronal network. The classical neurotransmitters GABA and glutamate are...
13.
Moore A, Coolen L, Porter D, Goodman R, Lehman M
Endocrinology . 2018 Jul; 159(9):3219-3234. PMID: 30010844
In the past decade since kisspeptin/neurokinin B/dynorphin (KNDy) cells were first identified in the mammalian hypothalamus, a plethora of new research has emerged adding insights into the role of this...
14.
Moore A, Prescott M, Czieselsky K, Desroziers E, Yip S, Campbell R, et al.
Endocrinology . 2018 Jul; 159(9):3200-3208. PMID: 30010812
GnRH neuron cell bodies are scattered throughout the basal forebrain but funnel their projections to the median eminence to release GnRH into the pituitary portal system to control fertility. Prior...
15.
Lehman M, Coolen L, Steiner R, Neal-Perry G, Wang L, Moenter S, et al.
J Neuroendocrinol . 2018 Apr; :e12600. PMID: 29656508
The 3 World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond" was held March 30-31 at the Rosen Centre Hotel in Orlando, Florida, providing an international forum for multidisciplinary scientists...
16.
Moore A, Lucas K, Goodman R, Coolen L, Lehman M
Sci Rep . 2018 Feb; 8(1):2242. PMID: 29396547
Kisspeptin/Neurokinin B/Dynorphin (KNDy) neurons of the arcuate nucleus (ARC) play a key role in the regulation of fertility. The ability to detect features of KNDy neurons that are essential for...
17.
Moore A, Campbell R
Front Neuroendocrinol . 2017 May; 46:1-14. PMID: 28551304
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and the leading cause of anovulatory infertility. Characterised by hyperandrogenism, menstrual dysfunction and polycystic ovaries, PCOS is a broad-spectrum disorder unlikely...
18.
Moore A, Campbell R
J Steroid Biochem Mol Biol . 2015 Oct; 160:106-17. PMID: 26455490
Polycystic ovary syndrome (PCOS) is a prevalent and distressing endocrine disorder lacking a clearly identified aetiology. Despite its name, PCOS may result from impaired neuronal circuits in the brain that...
19.
Moore A, Prescott M, Marshall C, Yip S, Campbell R
Proc Natl Acad Sci U S A . 2015 Jan; 112(2):596-601. PMID: 25550522
Polycystic ovarian syndrome (PCOS), the leading cause of female infertility, is associated with an increase in luteinizing hormone (LH) pulse frequency, implicating abnormal steroid hormone feedback to gonadotropin-releasing hormone (GnRH)...
20.
Moore A, Prescott M, Campbell R
Endocrinology . 2012 Dec; 154(2):796-806. PMID: 23254197
Gonadal steroid hormone feedback is impaired in polycystic ovarian syndrome (PCOS), a common endocrine disorder characterized by hyperandrogenism and an associated increase in LH pulse frequency. Using a prenatal androgen...