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Alecia T Dent

Explore the profile of Alecia T Dent including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 38
Followers 0
Related Specialties
Biochemistry
Pharmacology
Microbiology
Top 10 Co-Authors
Angela Wilks
William N Lanzilotta
Pierre Moenne-Loccoz
Therese Albert
Marley Brimberry
C Andrew Boswell
Christoph Spiess
Mary Ann T Go
Gregory Z Ferl
Madeleine K Ramos
Published In
J Biol Chem
Biochemistry
ACS Infect Dis
Mol Cancer Ther
Affiliations
Soon will be listed here.
Recent Articles
1.
Correction to "Axial Heme Coordination by the Tyr-His Motif in the Extracellular Hemophore HasAp Is Critical for the Release of Heme to the HasR Receptor of "
Dent A, Brimberry M, Albert T, Lanzilotta W, Moenne-Loccoz P, Wilks A
Biochemistry . 2021 Sep; 60(37):2844. PMID: 34505503
No abstract available.
2.
Axial Heme Coordination by the Tyr-His Motif in the Extracellular Hemophore HasAp Is Critical for the Release of Heme to the HasR Receptor of
Dent A, Brimberry M, Albert T, Lanzilotta W, Moenne-Loccoz P, Wilks A
Biochemistry . 2021 Jul; 60(33):2549-2559. PMID: 34324310
senses extracellular heme via an extra cytoplasmic function σ factor that is activated upon interaction of the hemophore holo-HasAp with the HasR receptor. Herein, we show Y75H holo-HasAp interacts with...
3.
Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration
Ramos M, Mandikian D, Sermeno L, King A, Dent A, Ho J, et al.
Mol Cancer Ther . 2021 Jul; 20(10):1956-1965. PMID: 34253591
T-cell-dependent bispecific antibodies (TDB) have been a major advancement in the treatment of cancer, allowing for improved targeting and efficacy for large molecule therapeutics. TDBs are comprised of one arm...
4.
Gallium(III)-Salophen as a Dual Inhibitor of Heme Sensing and Iron Acquisition
Centola G, Deredge D, Hom K, Ai Y, Dent A, Xue F, et al.
ACS Infect Dis . 2020 Jun; 6(8):2073-2085. PMID: 32551497
is an opportunistic bacterium that causes life-threatening infections in immunocompromised patients. In infection, it uses heme as a primary iron source and senses the availability of exogenous heme through the...
5.
Contributions of the heme coordinating ligands of the outer membrane receptor HasR to extracellular heme sensing and transport
Dent A, Wilks A
J Biol Chem . 2020 Jun; 295(30):10456-10467. PMID: 32522817
exhibits a high requirement for iron, which it can acquire via several mechanisms, including the acquisition and utilization of heme. The genome encodes two heme uptake systems, the heme assimilation...
6.
Post-transcriptional regulation of the heme assimilation system (Has) fine-tunes extracellular heme sensing
Dent A, Mourino S, Huang W, Wilks A
J Biol Chem . 2018 Dec; 294(8):2771-2785. PMID: 30593511
is an opportunistic pathogen that utilizes heme as a primary iron source within the host. Extracellular heme is sensed via a heme assimilation system () that encodes an extracytoplasmic function...