Alec J Batts
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Explore the profile of Alec J Batts including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
43
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Recent Articles
1.
Tsitsos F, Batts A, Jimenez D, Li C, Ji R, Bae S, et al.
bioRxiv
. 2025 Feb;
PMID: 39896565
Rationale: The characterization of microbubble activity has proven critical in assessing the safety and efficacy of ultrasound-mediated blood-brain barrier (BBB) opening and drug and gene delivery. In this study, we...
2.
Kline-Schoder A, Tsitsos F, Batts A, DiBenedetto M, Liu K, Bae S, et al.
bioRxiv
. 2025 Jan;
PMID: 39763821
The blood-brain barrier (BBB) limits drug delivery to the brain and the movement of neurological biomarkers between the brain and blood. Focused ultrasound-mediated blood-brain barrier opening (FUS-BBBO) noninvasively opens the...
3.
Bae S, Liu K, Pouliopoulos A, Ji R, Jimenez-Gambin S, Yousefian O, et al.
Theranostics
. 2024 Aug;
14(11):4519-4535.
PMID: 39113808
: Focused ultrasound (FUS) in combination with microbubbles has recently shown great promise in facilitating blood-brain barrier (BBB) opening for drug delivery and immunotherapy in Alzheimer's disease (AD). However, it...
4.
Bae S, Liu K, Pouliopoulos A, Ji R, Jimenez-Gambin S, Yousefian O, et al.
medRxiv
. 2024 Jan;
PMID: 38196636
Background: Focused ultrasound (FUS) in combination with microbubbles has recently shown great promise in facilitating blood-brain barrier (BBB) opening for drug delivery and immunotherapy in Alzheimer's disease (AD). However, it...
5.
Kline-Schoder A, Chintamen S, Willner M, DiBenedetto M, Noel R, Batts A, et al.
Nat Biomed Eng
. 2023 Oct;
8(5):650-663.
PMID: 37857722
The opening of the blood-brain barrier (BBB) by focused ultrasound (FUS) coupled with intravenously injected microbubbles can be leveraged as a form of immunotherapy for the treatment of neurodegenerative disorders....
6.
Noel R, Gorman S, Batts A, Konofagou E
Front Neurosci
. 2023 Aug;
17:1229683.
PMID: 37575309
The amyloid-β (Aβ) hypothesis implicates Aβ protein accumulation in Alzheimer's disease (AD) onset and progression. However, therapies targeting Aβ have proven insufficient in achieving disease reversal, prompting a shift to...
7.
Batts A, Ji R, Noel R, Kline-Schoder A, Bae S, Kwon N, et al.
Theranostics
. 2023 Feb;
13(3):1180-1197.
PMID: 36793858
Focused ultrasound (FUS)-mediated blood-brain barrier (BBB) opening is a noninvasive, safe and reversible technique for targeted drug delivery to the brain. Most preclinical systems developed to perform and monitor BBB...
8.
Pouliopoulos A, Murillo M, Noel R, Batts A, Ji R, Kwon N, et al.
Brain Stimul
. 2022 Jun;
15(4):927-941.
PMID: 35718324
Optogenetics has revolutionized the capability of controlling genetically modified neurons in vitro and in vivo and has become an indispensable neuroscience tool. Using light as a probe for selective neuronal...
9.
Sheybani N, Batts A, Mathew A, Thim E, Price R
Theranostics
. 2020 Jul;
10(16):7436-7447.
PMID: 32642004
: Increasing evidence points to the critical role of extracellular vesicles (EVs) as molecular parcels that carry a diverse array of bioactive payloads for coordination of complex intracellular signaling. Focused...