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Elisa E Konofagou

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Articles 230
Citations 4977
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Recent Articles
1.
Gami P, Roy T, Liang P, Kemper P, Travagliati M, Baldasarre L, et al.
IEEE Trans Biomed Eng . 2025 Mar; PP. PMID: 40085470
Objective: Piezoelectric micromachined ultrasound transducer (pMUT) technology shows promise for wearable ultrasound applications, although with limitations in acquisition performance compared to standard transducers. To translate Pulse Wave Imaging (PWI)-an ultrasound...
2.
Noel R, Kugelman T, Karakatsani M, Shahriar S, Willner M, Choi C, et al.
bioRxiv . 2025 Feb; PMID: 39975117
Significance Statement: Focused ultrasound with microbubbles is used as a noninvasive method to safely open the BBB at low acoustic pressures for therapeutic delivery into the CNS, but the mechanisms...
3.
Tsitsos F, Batts A, Jimenez D, Li C, Ji R, Bae S, et al.
bioRxiv . 2025 Feb; PMID: 39896565
Rationale: The characterization of microbubble activity has proven critical in assessing the safety and efficacy of ultrasound-mediated blood-brain barrier (BBB) opening and drug and gene delivery. In this study, we...
4.
Liu D, Xin Z, Ji R, Tsitsos F, Jimenez-Gambin S, Konofagou E, et al.
Proc IEEE Int Symp Biomed Imaging . 2025 Jan; 2024. PMID: 39844940
Utilizing a multi-task deep learning framework, this study generated synthetic CT (sCT) images from a limited dataset of Ultrashort echo time (UTE) MRI for transcranial focused ultrasound (tFUS) planning. A...
5.
Kline-Schoder A, Tsitsos F, Batts A, DiBenedetto M, Liu K, Bae S, et al.
bioRxiv . 2025 Jan; PMID: 39763821
The blood-brain barrier (BBB) limits drug delivery to the brain and the movement of neurological biomarkers between the brain and blood. Focused ultrasound-mediated blood-brain barrier opening (FUS-BBBO) noninvasively opens the...
6.
Grondin J, Schleifer H, Weber R, Lee C, Tourni M, Konofagou E
PLoS One . 2024 Dec; 19(12):e0313410. PMID: 39729494
Background: Imaging both electrical and mechanical cardiac function can better characterize cardiac disease and improve patient care. Currently, there is no noninvasive technique that can simultaneously image both electrical and...
7.
Liu Y, Hossain M, Li X, Konofagou E
Ultrasound Med Biol . 2024 Oct; 51(1):169-179. PMID: 39428259
Objective: Elastography images tissue mechanical responses and infers the underlying properties to aid diagnosis and treatment response monitoring. The estimation of absolute or relative tumor properties may vary with dimensions...
8.
Jimenez-Gambin S, Bae S, Ji R, Tsitsos F, Konofagou E
IEEE Trans Ultrason Ferroelectr Freq Control . 2024 Aug; 71(10):1172-1185. PMID: 39196737
Focused ultrasound (FUS) and microbubbles facilitate blood-brain barrier opening (BBBO) noninvasively, transiently, and safely for targeted drug delivery. Unlike state-of-the-art approaches, in this study, we demonstrate for the first time...
9.
Bae S, Liu K, Pouliopoulos A, Ji R, Jimenez-Gambin S, Yousefian O, et al.
Theranostics . 2024 Aug; 14(11):4519-4535. PMID: 39113808
: Focused ultrasound (FUS) in combination with microbubbles has recently shown great promise in facilitating blood-brain barrier (BBB) opening for drug delivery and immunotherapy in Alzheimer's disease (AD). However, it...
10.
Kim S, Kwon N, Hossain M, Bendig J, Konofagou E
Neuroimage . 2024 Aug; 298:120768. PMID: 39096984
Focused ultrasound (FUS) stimulation is a promising neuromodulation technique with the merits of non-invasiveness, high spatial resolution, and deep penetration depth. However, simultaneous imaging of FUS-induced brain tissue displacement and...