Ale Narvanen
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Explore the profile of Ale Narvanen including associated specialties, affiliations and a list of published articles.
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56
Citations
480
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Recent Articles
1.
Wen H, Narvanen A, Jokivarsi K, Poutiainen P, Xu W, Lehto V
Int J Pharm
. 2022 Jul;
624:122040.
PMID: 35902052
Nuclear medicine imaging plays an important role in nanomedicine. However, it is still challenging to develop a versatile platform to make the nonviral nanovectors used in cancer therapy biotraceable. In...
2.
Thapa R, Mondal S, Riikonen J, Rantanen J, Nakki S, Nissinen T, et al.
PLoS Negl Trop Dis
. 2021 Jun;
15(6):e0009533.
PMID: 34185780
Visceral leishmaniasis is a vector-borne protozoan infection that is fatal if untreated. There is no vaccination against the disease, and the current chemotherapeutic agents are ineffective due to increased resistance...
3.
Tamarov K, Xu W, Osminkina L, Zinovyev S, Soininen P, Kudryavtsev A, et al.
J Control Release
. 2016 Oct;
241:220-228.
PMID: 27686581
Toc Image: The temperature responsive (TR) polymer grafted on the surface of porous silicon nanoparticles (PSi NPs) changes its conformation in response to the heating induced by infrared or radiofrequency...
4.
Koistinen H, Wallen E, Ylikangas H, Meinander K, Lahtela-Kakkonen M, Narvanen A, et al.
Biol Chem
. 2016 Jul;
397(12):1229-1235.
PMID: 27383882
Kallikrein-related peptidase-3 (KLK3, known also as prostate-specific antigen, PSA) is highly expressed in the prostate. KLK3 possess antiangiogenic activity, which we have found to be related to its proteolytic activity....
5.
Kuosmanen S, Viitala S, Laitinen T, Perakyla M, Polonen P, Kansanen E, et al.
Nucleic Acids Res
. 2016 Jan;
44(4):1760-75.
PMID: 26826707
Transcription factor binding specificity is crucial for proper target gene regulation. Motif discovery algorithms identify the main features of the binding patterns, but the accuracy on the lower affinity sites...
6.
Xu W, Thapa R, Liu D, Nissinen T, Granroth S, Narvanen A, et al.
Mol Pharm
. 2015 Sep;
12(11):4038-47.
PMID: 26390039
In spite of the advances in drug delivery, the preparation of smart nanocomposites capable of precisely controlled release of multiple drugs for sequential combination therapy is still challenging. Here, a...
7.
Kaasalainen M, Rytkonen J, Makila E, Narvanen A, Salonen J
Langmuir
. 2015 Jan;
31(5):1722-9.
PMID: 25604519
Porous silicon (PSi) nanoparticles' tunable properties are facilitating their use at highly challenging medical tasks such as peptide delivery. Because of many different mechanisms that are affecting the interaction between...
8.
Wang C, Makila E, Bonduelle C, Rytkonen J, Raula J, Almeida S, et al.
ACS Appl Mater Interfaces
. 2014 Dec;
7(3):2006-15.
PMID: 25539741
Porous silicon (PSi) nanomaterials combine a high drug loading capacity and tunable surface chemistry with various surface modifications to meet the requirements for biomedical applications. In this work, alkyne-terminated thermally...
9.
Nakki S, Rytkonen J, Nissinen T, Florea C, Riikonen J, Ek P, et al.
Acta Biomater
. 2014 Dec;
13:207-15.
PMID: 25463492
Nanotechnology has attracted considerable interest in the field of biomedicine, where various nanoparticles (NPs) have been introduced as efficient drug carrier systems. Mesoporous silicon (PSi) is one of the most...
10.
Mattsson J, Ravela S, Hekim C, Jonsson M, Malm J, Narvanen A, et al.
PLoS One
. 2014 Sep;
9(9):e107819.
PMID: 25237904
Prostate-specific antigen (PSA or kallikrein-related peptidase-3, KLK3) exerts chymotrypsin-like proteolytic activity. The main biological function of PSA is the liquefaction of the clot formed after ejaculation by cleavage of semenogelins...