Albert Santamaria-Martinez
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Explore the profile of Albert Santamaria-Martinez including associated specialties, affiliations and a list of published articles.
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16
Citations
902
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Recent Articles
1.
Santamaria-Martinez A, Epiney J, Srivastava D, Tavernari D, Varrone M, Milowich D, et al.
Nat Commun
. 2024 Dec;
15(1):10650.
PMID: 39653701
The efficacy of anti-cancer therapies depends on the genomic composition of the tumor, its microenvironment, spatial organization, and intra-tumor heterogeneity. B-cell lymphomas are a heterogeneous group of tumors emerging from...
2.
Petruzzella A, Bruand M, Santamaria-Martinez A, Katanayeva N, Reymond L, Wehrle S, et al.
Nat Chem Biol
. 2024 May;
20(9):1188-1198.
PMID: 38811854
Cysteine cathepsins are a family of proteases that are relevant therapeutic targets for the treatment of different cancers and other diseases. However, no clinically approved drugs for these proteins exist,...
3.
Varrone M, Tavernari D, Santamaria-Martinez A, Walsh L, Ciriello G
Nat Genet
. 2023 Dec;
56(1):74-84.
PMID: 38066188
Tissues are organized in cellular niches, the composition and interactions of which can be investigated using spatial omics technologies. However, systematic analyses of tissue composition are challenged by the scale...
4.
Young C, Beziaud L, Dessen P, Madurga Alonso A, Santamaria-Martinez A, Huelsken J
Nat Commun
. 2023 Nov;
14(1):7076.
PMID: 37925484
Understanding the mechanisms that enable cancer cells to metastasize is essential in preventing cancer progression. Here we examine the metabolic adaptations of metastasis-initiating cells (MICs) in female breast cancer and...
5.
Fico F, Santamaria-Martinez A
Cancers (Basel)
. 2020 Dec;
12(12).
PMID: 33371274
Tumor progression involves the co-evolution of transformed cells and the milieu in which they live and expand. Breast cancer stem cells (BCSCs) are a specialized subset of cells that sustain...
6.
Fico F, Santamaria-Martinez A
Mol Oncol
. 2020 Oct;
14(12):3198-3210.
PMID: 33080107
Breast cancer metastasis is a complex process that depends not only on intrinsic characteristics of metastatic stem cells, but also on the particular microenvironment that supports their growth and modulates...
7.
Dafflon C, Santamaria-Martinez A, Ordonez-Moran P
Methods Mol Biol
. 2020 Jul;
2171:293-302.
PMID: 32705651
In many tumor types, only a minor pool of cancer cells-the so-called cancer stem cells-is able to colonize distant organs and give rise to secondary tumors. In humans, the liver...
8.
Alday-Parejo B, Richard F, Worthmuller J, Rau T, Galvan J, Desmedt C, et al.
Cancers (Basel)
. 2020 Jan;
12(1).
PMID: 31963297
Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin....
9.
Fico F, Bousquenaud M, Ruegg C, Santamaria-Martinez A
Stem Cell Reports
. 2019 Jul;
13(1):1-9.
PMID: 31257133
Cancer stem cells (CSCs) are defined by their ability to regenerate a tumor upon transplantation. However, it is not yet clear whether tumors contain a single CSC population or different...
10.
Bousquenaud M, Fico F, Solinas G, Ruegg C, Santamaria-Martinez A
Breast Cancer Res
. 2018 Sep;
20(1):104.
PMID: 30180888
Background: Obesity is a strong predictor of poor prognosis in breast cancer, especially in postmenopausal women. In particular, tumors in obese patients tend to seed more distant metastases, although the...