Alastair V Ferguson
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Explore the profile of Alastair V Ferguson including associated specialties, affiliations and a list of published articles.
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84
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1554
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Recent Articles
1.
Fry W, Ferguson A
Handb Clin Neurol
. 2021 Jul;
180:203-215.
PMID: 34225930
In this chapter, we review the extensive literature describing the roles of the subfornical organ (SFO), the organum vasculosum of the terminalis (OVLT), and the median preoptic nucleus (MnPO), comprising...
2.
Brzezinska P, Simpson N, Hubert F, Jacobs A, Umana M, MacKeil J, et al.
J Biol Chem
. 2021 Mar;
296:100606.
PMID: 33789162
In addition to maintaining cellular ER Ca stores, store-operated Ca entry (SOCE) regulates several Ca-sensitive cellular enzymes, including certain adenylyl cyclases (ADCYs), enzymes that synthesize the secondary messenger cyclic AMP...
3.
Grover H, Smith P, Ferguson A
J Neuroendocrinol
. 2020 May;
32(6):e12855.
PMID: 32436241
Phoenixin (PNX) is a neuropeptide shown to play roles in the control of reproduction. The nucleus of the solitary tract (NTS), a critical autonomic integrating centre in the hindbrain, is...
4.
Dos-Santos R, Reis L, Perello M, Ferguson A, Mecawi A
Ann N Y Acad Sci
. 2019 Apr;
1455(1):81-97.
PMID: 31008525
Ghrelin is a peptide mainly produced and secreted by the stomach. Since its discovery, the impact of ghrelin on the regulation of food intake has been the most studied function...
5.
Paes-Leme B, Dos-Santos R, Mecawi A, Ferguson A
J Neuroendocrinol
. 2018 Oct;
30(12):e12654.
PMID: 30365188
The subfornical organ (SFO) lacks the normal blood-brain barrier and senses the concentrations of many different circulating signals, including glucose and angiotensin II (ANG II). ANG II has recently been...
6.
Dos-Santos R, Grover H, Reis L, Ferguson A, Mecawi A
Front Cell Neurosci
. 2018 Sep;
12:275.
PMID: 30210300
The paraventricular nucleus (PVN) is involved in the control of sympathetic tone and the secretion of hormones, both functions known to be influenced by ghrelin, suggesting direct effect of ghrelin...
7.
Medlock L, Shute L, Fry M, Standage D, Ferguson A
J Neurophysiol
. 2018 Aug;
120(5):2269-2281.
PMID: 30089060
Subfornical organ (SFO) neurons exhibit heterogeneity in current expression and spiking behavior, where the two major spiking phenotypes appear as tonic and burst firing. Insight into the mechanisms behind this...
8.
Black E, Smith P, McIsaac W, Ferguson A
Physiol Rep
. 2018 May;
6(10):e13704.
PMID: 29802680
Brain-derived neurotrophic factor (BDNF), a neurotrophin traditionally associated with neural plasticity, has more recently been implicated in fluid balance and cardiovascular regulation. It is abundantly expressed in both the central...
9.
Simpson N, Ferguson A
Am J Physiol Regul Integr Comp Physiol
. 2018 Apr;
315(3):R425-R433.
PMID: 29668324
Inflammation is thought to play a fundamental role in the pathophysiology of hypertension and heart failure, although the mechanisms for this remain unclear. Proinflammatory cytokines, such as tumor necrosis factor-α...
10.
Gasparini S, Stein L, Loewen S, Haddock C, Soo J, Ferguson A, et al.
Am J Physiol Regul Integr Comp Physiol
. 2018 Jan;
314(4):R623-R628.
PMID: 29364701
The newly described hypothalamic peptide, phoenixin, is produced in the hypothalamus and adenohypophysis, where it acts to control reproductive hormone secretion. Both phoenixin and its receptor GPR173 are expressed in...