Alan H Roter
Overview
Explore the profile of Alan H Roter including associated specialties, affiliations and a list of published articles.
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5
Citations
532
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0
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Recent Articles
1.
Mizrahi-Man O, Woehrmann M, Webster T, Gollub J, Bivol A, Keeble S, et al.
PLoS One
. 2022 Nov;
17(11):e0277680.
PMID: 36395175
The UK Biobank genotyped about 500k participants using Applied Biosystems Axiom microarrays. Participants were subsequently sequenced by the UK Biobank Exome Sequencing Consortium. Axiom genotyping was highly accurate in comparison...
2.
Shi L, Campbell G, Jones W, Campagne F, Wen Z, Walker S, et al.
Nat Biotechnol
. 2010 Aug;
28(8):827-38.
PMID: 20676074
Gene expression data from microarrays are being applied to predict preclinical and clinical endpoints, but the reliability of these predictions has not been established. In the MAQC-II project, 36 independent...
3.
Natsoulis G, Pearson C, Gollub J, P Eynon B, Ferng J, Nair R, et al.
Mol Syst Biol
. 2008 Mar;
4:175.
PMID: 18364709
We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound-treated rats. Thirty-four distinct signatures (classifiers) for pharmacological and toxicological end points...
4.
Ganter B, Tugendreich S, Pearson C, Ayanoglu E, Baumhueter S, Bostian K, et al.
J Biotechnol
. 2005 Jul;
119(3):219-44.
PMID: 16005536
Successful drug discovery requires accurate decision making in order to advance the best candidates from initial lead identification to final approval. Chemogenomics, the use of genomic tools in pharmacology and...
5.
Roter A
Curr Opin Drug Discov Devel
. 2005 May;
8(3):309-15.
PMID: 15892245
Over the past 15 years, genomics, combinatorial chemistry and high-throughput automation have transformed the setting for drug discovery, from an information-poor to a data-rich environment. The next challenge for informatics...