Alan Fotoohi
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Explore the profile of Alan Fotoohi including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
38
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Recent Articles
1.
Salmani M, Ghaderi B, Fotoohi A, Omid-Shafaat R, Vahabzadeh Z, Fotouhi O, et al.
Cancer Chemother Pharmacol
. 2022 Sep;
90(5):389-397.
PMID: 36083300
Purpose: Fluoropyrimidines, the major chemotherapeutic agents in various malignancies treatment, are metabolized by dihydropyrimidine dehydrogenase (DPD). DPD deficiency can lead to severe and sometimes fatal toxicity. In the present study,...
2.
Ahmed J, Makonnen E, Bisaso R, Mukonzo J, Fotoohi A, Aseffa A, et al.
Front Pharmacol
. 2020 May;
11:406.
PMID: 32390827
Cyclophosphamide (CPA) containing chemotherapy regimen is the standard of care for breast cancer treatment in sub-Saharan Africa. Wide inter-individual variations in pharmacokinetics (PK) of cyclophosphamide (CPA) influence the efficacy and...
3.
Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients
Ahmed J, Makonnen E, Fotoohi A, Aseffa A, Howe R, Aklillu E
Cancers (Basel)
. 2019 Sep;
11(9).
PMID: 31547390
Tamoxifen displays wide inter-individual variability (IIV) in its pharmacokinetics and treatment outcome. Data on tamoxifen pharmacokinetics and pharmacogenetics from black African breast cancer patient populations is lacking. We investigated the...
4.
Ahmed J, Makonnen E, Yimer G, Seifu D, Bekele A, Assefa M, et al.
Front Pharmacol
. 2019 May;
10:481.
PMID: 31139078
Chemotherapy-induced hematologic toxicity is the primary reasons of dose reductions and/or delays, low relative dose intensity (RDI), and predicts anticancer response. We investigated the incidence and predictors of chemotherapy-induced hematologic...
5.
Ahmed J, Makonnen E, Fotoohi A, Yimer G, Seifu D, Assefa M, et al.
Nutrients
. 2019 Feb;
11(2).
PMID: 30699973
Emerging evidence associates vitamin D deficiency and vitamin D receptor () genetic variations with risk for breast cancer. This study investigated the prevalence of vitamin D deficiency and its association...
6.
Karim H, Appell M, Fotoohi A
J Chromatogr B Analyt Technol Biomed Life Sci
. 2013 Oct;
939:80-5.
PMID: 24113235
Thiopurine efficacy is partly reflected by the genetic polymorphism of the thiopurine methyltransferase (TPMT) enzyme, which is responsible for variation in the metabolism, toxicity and therapeutic efficacy of the thiopurines...