Alan D Michelson
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Explore the profile of Alan D Michelson including associated specialties, affiliations and a list of published articles.
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139
Citations
3048
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Recent Articles
11.
Revel-Vilk S, Naamad M, Frydman D, Freund M, Dinur T, Istaiti M, et al.
Thromb Haemost
. 2021 Sep;
122(6):951-960.
PMID: 34507369
Objectives: Patients with Gaucher disease (GD) are at increased risk of bleeding and have varying degrees of thrombocytopenia, making the analysis of platelet function difficult. This study aimed to provide...
12.
Spurgeon B, Linden M, Michelson A, Frelinger 3rd A
Curr Protoc
. 2021 Jun;
1(6):e178.
PMID: 34170638
Platelets are small but very abundant blood cells that play a key role in hemostasis, contributing to thrombus formation at sites of injury. The ability of platelets to perform this...
13.
Spurgeon B, Michelson A, Frelinger 3rd A
Curr Protoc
. 2021 May;
1(5):e112.
PMID: 33950581
Platelets are small blood cells that contribute to hemostasis, immunity, and inflammation. Characterization of platelet surface markers allows for differentiation of activated platelets from resting platelets, diagnosis of platelet disorders,...
14.
Neculaes B, Frelinger 3rd A, Gerrits A, Gremmel T, Forde E, Klopman S, et al.
PLoS One
. 2021 Apr;
16(4):e0249209.
PMID: 33891598
Activated platelet-rich plasma (PRP) has been used in the clinical settings of wound healing and regenerative medicine, with activation typically induced by the addition of bovine thrombin. To eliminate issues...
15.
Wahlster L, Verboon J, Ludwig L, Black S, Luo W, Garg K, et al.
J Exp Med
. 2021 Apr;
218(6).
PMID: 33857290
Advances in genome sequencing have resulted in the identification of the causes for numerous rare diseases. However, many cases remain unsolved with standard molecular analyses. We describe a family presenting...
16.
Spurgeon B, Michelson A, Frelinger 3rd A
Cytometry A
. 2021 Jan;
99(2):170-179.
PMID: 33399275
Platelets mediate key biological processes, including hemostasis, immunity, and inflammation. Although platelets are often treated as a homogeneous cell population, they are known to be heterogeneous in size, age, surface...
17.
Croteau S, Frelinger 3rd A, Gerrits A, Michelson A
J Thromb Haemost
. 2020 Dec;
19(4):976-982.
PMID: 33370471
Background: Bleeding phenotypes among individuals with severe factor VIII (FVIII) deficiency are variable, even with routine prophylactic FVIII administration. Activated platelets, in addition to their role in primary hemostasis, play...
18.
Mazzeffi M, Tanaka K, Wu Y, Zhang A, Kareddy N, Tito E, et al.
Platelets
. 2020 Dec;
33(1):116-122.
PMID: 33284729
Our objective was to characterize platelet surface glycoprotein (GP)Ibα, activated GPIIb-IIIa, and -selectin levels during and after extracorporeal membrane oxygenation (ECMO). We performed a single center cohort study of 10...
19.
Pittman D, Hines P, Beidler D, Rybin D, Frelinger A, Michelson A, et al.
Blood
. 2020 Oct;
137(15):2010-2020.
PMID: 33067606
Clinical trials in sickle cell disease (SCD) often focus on health care utilization for painful vaso-occlusive crises (VOCs). However, no objective, quantifiable pain biomarkers exist, pain is not specific to...
20.
Sims M, Mayer L, Collins J, Bariana T, Megy K, Lavenu-Bombled C, et al.
Blood
. 2020 Jul;
136(17):1956-1967.
PMID: 32693407
Gray platelet syndrome (GPS) is a rare recessive disorder caused by biallelic variants in NBEAL2 and characterized by bleeding symptoms, the absence of platelet α-granules, splenomegaly, and bone marrow (BM)...