Alan D Michelson
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Explore the profile of Alan D Michelson including associated specialties, affiliations and a list of published articles.
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139
Citations
3048
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Recent Articles
1.
Michelson A, Frelinger Iii A, Haynes R, Kinney H, Gremmel T
Semin Thromb Hemost
. 2024 Jun;
50(8):1187-1190.
PMID: 38889800
No abstract available.
2.
Frelinger 3rd A, Haynes R, Goldstein R, Berny-Lang M, Gerrits A, Riehs M, et al.
Sci Rep
. 2024 May;
14(1):11092.
PMID: 38750089
Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal infant mortality, but the underlying cause(s) are unclear. A subset of SIDS infants has abnormalities in the neurotransmitter, serotonin...
3.
Gremmel T, Frelinger 3rd A, Michelson A
Semin Thromb Hemost
. 2024 Apr;
50(8):1173-1186.
PMID: 38653463
Platelets are the smallest blood cells, numbering 150 to 350 × 10/L in healthy individuals. The ability of activated platelets to adhere to an injured vessel wall and form aggregates...
4.
Heeney M, Abboud M, Githanga J, Inusa B, Kanter J, Michelson A, et al.
Blood
. 2022 Jul;
140(13):1470-1481.
PMID: 35849650
The phase 3 HESTIA3 study assessed the efficacy and safety of the reversible P2Y12 inhibitor ticagrelor vs placebo in preventing vaso-occlusive crises in pediatric patients with sickle cell disease (SCD)....
5.
Poli V, Gioia M, Sola-Visner M, Granucci F, Frelinger 3rd A, Michelson A, et al.
Immunity
. 2022 Jan;
55(2):224-236.e5.
PMID: 34995475
During gram-negative septicemia, interactions between platelets and neutrophils initiate a detrimental feedback loop that sustains neutrophil extracellular trap (NET) induction, disseminated intravascular coagulation, and inflammation. Understanding intracellular pathways that control...
6.
Hardin J, Michelson A, McCrindle B, Miriam Pina L, Peluso C, Simpkins P, et al.
Clin Ther
. 2021 Dec;
43(12):2074-2087.
PMID: 34872740
Purpose: Children generally have a lower risk of venous thromboembolism (VTE) than adults, but those with acute and chronic conditions requiring hospitalization and surgical procedures are at increased risk. Anticoagulant...
7.
Gremmel T, Michelson A, Wadowski P, Pultar J, Weikert C, Tscharre M, et al.
Atherosclerosis
. 2021 Nov;
339:12-19.
PMID: 34808540
Background And Aims: Protease-activated receptor (PAR)-1-mediated platelet activation may vary according to sex and clinical situation. In order to investigate sex-specific platelet activation through PAR-1, we assessed platelet response to...
8.
Frelinger 3rd A, Rivera J, Connor D, Freson K, Greinacher A, Harrison P, et al.
J Thromb Haemost
. 2021 Sep;
19(12):3193-3202.
PMID: 34580997
Flow cytometry is increasingly used in the study of platelets in inherited and acquired disorders of platelet number and function. However, wide variation exists in specific reagents, methods, and equipment...
9.
McCrindle B, Michelson A, Van Bergen A, Suzana Horowitz E, Sandoval J, Justino H, et al.
J Am Heart Assoc
. 2021 Sep;
10(22):e021765.
PMID: 34558312
Background Patients with single-ventricle physiology who undergo the Fontan procedure are at risk for thrombotic events associated with significant morbidity and mortality. The UNIVERSE Study evaluated the efficacy and safety...
10.
Zhu P, Willmann S, Zhou W, Yang H, Michelson A, McCrindle B, et al.
J Clin Pharmacol
. 2021 Sep;
62(2):220-231.
PMID: 34524700
Thrombosis remains an important complication for children with single-ventricle physiology following the Fontan procedure, and effective thromboprophylaxis is an important unmet medical need. To obviate conventional dose-finding studies and expedite...