Alain Wuethrich
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Explore the profile of Alain Wuethrich including associated specialties, affiliations and a list of published articles.
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59
Citations
311
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Recent Articles
1.
Zhang Z, Wang J, Wuethrich A, Trau M
Natl Sci Rev
. 2025 Feb;
12(3):nwae452.
PMID: 39926198
The epithelial-mesenchymal transition (EMT) is a critical process for cancer to metastasize by promoting invasiveness and dissemination of cancer cells in the body. Understanding and tracking EMT could improve cancer...
2.
Sinclair J, Vedelago C, Ryan F, Carney M, Redd M, Lynn M, et al.
Nat Microbiol
. 2024 Oct;
9(12):3135-3147.
PMID: 39478108
An estimated 65 million people globally suffer from post-acute sequelae of COVID-19 (PASC), with many experiencing cardiovascular symptoms (PASC-CVS) like chest pain and heart palpitations. This study examines the role...
3.
Liao C, Wu Z, Lin C, Chen X, Zou Y, Zhao W, et al.
Smart Med
. 2024 Aug;
2(1):e20220020.
PMID: 39188554
Prostate cancer remains the second-most common cancer diagnosed in men, despite the increasingly widespread use of serum prostate-specific antigen (PSA) screening. The controversial clinical implications and cost benefits of PSA...
4.
Zhou Q, Niu X, Zhang Z, OByrne K, Kulasinghe A, Fielding D, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(33):e2401818.
PMID: 38885350
Glycosylation is the most common post-translational modification of proteins and regulates a myriad of fundamental biological processes under normal, and pathological conditions. Altered protein glycosylation is linked to malignant transformation,...
5.
Shanmugasundaram K, Ahmed E, Miao X, Kulasinghe A, Fletcher J, Monkman J, et al.
ACS Sens
. 2024 Jun;
9(6):3009-3016.
PMID: 38836608
Immune checkpoint inhibitors (ICIs) targeting programmed cell death ligand 1 (PD-L1), or its receptor, PD-1 have improved survival in patients with non-small-cell lung cancer (NSCLC). Assessment of PD-L1 expression requires...
6.
Li J, Li M, Wuethrich A, Guan R, Zhao L, Hu C, et al.
Anal Chem
. 2024 May;
96(19):7651-7660.
PMID: 38690989
Development of molecular diagnostics for lung cancer stratification and monitoring is crucial for the rational planning and timely adjustment of treatments to improve clinical outcomes. In this regard, we propose...
7.
Li J, Guan R, Wuethrich A, Yan M, Cheng J, Liu G, et al.
Anal Chem
. 2024 Mar;
96(11):4495-4504.
PMID: 38445954
The molecular detection of multiple respiratory viruses provides evidence for the rational use of drugs and effective health management. Herein, we developed and tested the clinical performance of an electrohydrodynamic-driven...
8.
9.
Niu X, Zhang Z, Zhou Q, Wuethrich A, Lobb R, Trau M
Proteomics
. 2024 Feb;
24(11):e2300094.
PMID: 38343172
Microglia are a specialized population of innate immune cells located in the central nervous system. In response to physiological and pathological changes in their microenvironment, microglia can polarize into pro-inflammatory...
10.
Zhou Q, Wang J, Zhang Z, Wuethrich A, Lobb R, Trau M
Biosens Bioelectron
. 2023 Nov;
244:115819.
PMID: 37952322
Melanoma continues to be a leading cause of mortality among skin cancers. Despite advancements in targeted therapy, patients frequently develop resistance, leading to disease progression within a year. This resistance...