Alain Dabdoub
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Explore the profile of Alain Dabdoub including associated specialties, affiliations and a list of published articles.
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1796
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Recent Articles
1.
Thulasiram M, Yamamoto R, Olszewski R, Gu S, Morell R, Hoa M, et al.
iScience
. 2025 Mar;
28(2):111832.
PMID: 40028281
The stria vascularis (SV) is an essential component of the inner ear that regulates the ionic environment required for hearing. SV degeneration disrupts cochlear homeostasis, leading to irreversible hearing loss,...
2.
Miao D, Wilke M, Pham J, Ladha F, Singh M, Arsenio J, et al.
Hum Genomics
. 2024 Oct;
18(1):112.
PMID: 39380081
Background: Cisplatin-induced ototoxicity (CIO), characterized by irreversible and progressive bilateral hearing loss, is a prevalent adverse effect of cisplatin chemotherapy. Alongside clinical risk factors, genetic variants contribute to CIO and...
3.
Thulasiram M, Yamamoto R, Olszewski R, Gu S, Morell R, Hoa M, et al.
bioRxiv
. 2024 May;
PMID: 38712156
Summary: The stria vascularis (SV), part of the blood-labyrinth barrier, is an essential component of the inner ear that regulates the ionic environment required for hearing. SV degeneration disrupts cochlear...
4.
Zhang Y, Neng L, Sharma K, Hou Z, Johnson A, Song J, et al.
Elife
. 2023 Jan;
12.
PMID: 36719173
The inner ear has a rich population of pericytes, a multi-functional mural cell essential for sensory hair cell heath and normal hearing. However, the mechanics of how pericytes contribute to...
5.
Ogier J, Gao Y, Dunne E, Wilson M, Ranganathan S, Tesch G, et al.
J Mol Med (Berl)
. 2022 May;
100(5):815.
PMID: 35536324
No abstract available.
6.
Ogier J, Gao Y, Dunne E, Wilson M, Ranganathan S, Tesch G, et al.
J Mol Med (Berl)
. 2022 Apr;
100(5):797-813.
PMID: 35471608
Aminoglycoside antibiotics are lifesaving medicines, crucial for the treatment of chronic or drug resistant infections. However, aminoglycosides are toxic to the sensory hair cells in the inner ear. As a...
7.
Thulasiram M, Ogier J, Dabdoub A
Front Cell Dev Biol
. 2022 Mar;
10:841708.
PMID: 35309932
The stria vascularis (SV) is a highly vascularized tissue lining the lateral wall of the cochlea. The SV maintains cochlear fluid homeostasis, generating the endocochlear potential that is required for...
8.
Mahshid S, Higazi A, Ogier J, Dabdoub A
Adv Sci (Weinh)
. 2021 Dec;
9(9):e2104033.
PMID: 34957708
Rapid diagnostic testing has become a mainstay of patient care, using easily obtained samples such as blood or urine to facilitate sample analysis at the point-of-care. These tests rely on...
9.
Mahshid S, Dabdoub A
Biosens Bioelectron
. 2020 Jul;
165:112369.
PMID: 32729501
Current approaches for diagnosis of hearing or vestibular disorders are mostly based on physical examinations that cannot provide information about the exact location of cellular damage inside the inner ear....
10.
Samarajeewa A, Jacques B, Dabdoub A
Mol Ther
. 2019 Apr;
27(5):904-911.
PMID: 30982678
Hearing loss is one of the most prevalent sensory deficits worldwide and can result from the death of mechanosensory hair cells that transduce auditory signals in the cochlea. The mammalian...