Alain C Borczuk
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Explore the profile of Alain C Borczuk including associated specialties, affiliations and a list of published articles.
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127
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5232
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Recent Articles
11.
Rendeiro A, Ravichandran H, Kim J, Borczuk A, Elemento O, Schwartz R
medRxiv
. 2022 Dec;
PMID: 36482970
SARS-CoV-2 infection can manifest as a wide range of respiratory and systemic symptoms well after the acute phase of infection in over 50% of patients. Key questions remain on the...
12.
Borczuk A, Yantiss R
J Biomed Sci
. 2022 Oct;
29(1):87.
PMID: 36289507
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably severe pulmonary symptoms, cardiac conduction abnormalities, diarrhea, and gastrointestinal bleeding,...
13.
He Y, Kim I, Bian J, Polyzos A, Di Giammartino D, Zhang Y, et al.
J Thorac Oncol
. 2022 Sep;
17(12):1375-1386.
PMID: 36049655
Introduction: The pathogenesis of thymic epithelial tumors remains largely unknown. We previously identified GTF2I L424H as the most frequently recurrent mutation in thymic epithelial tumors. Nevertheless, the precise role of...
14.
Frere J, Serafini R, Pryce K, Zazhytska M, Oishi K, Golynker I, et al.
Sci Transl Med
. 2022 Jul;
14(664):eabq3059.
PMID: 35857629
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in prolonged pathologies collectively referred to as post-acute sequalae of COVID-19 (PASC) or long COVID. To...
15.
Kato T, Asakura T, Edwards C, Dang H, Mikami Y, Okuda K, et al.
Am J Respir Crit Care Med
. 2022 Jul;
206(11):1336-1352.
PMID: 35816430
The incidence and sites of mucus accumulation and molecular regulation of mucin gene expression in coronavirus (COVID-19) lung disease have not been reported. To characterize the incidence of mucus accumulation...
16.
Price D, Benedetti E, Hoffman K, Gomez-Escobar L, Alvarez-Mulett S, Capili A, et al.
Am J Pathol
. 2022 Apr;
192(7):1001-1015.
PMID: 35469796
Vascular injury is a well-established, disease-modifying factor in acute respiratory distress syndrome (ARDS) pathogenesis. Recently, coronavirus disease 2019 (COVID-19)-induced injury to the vascular compartment has been linked to complement activation,...
17.
Altorki N, Borczuk A, Harrison S, Groner L, Bhinder B, Mittal V, et al.
Cell Rep
. 2022 Apr;
39(1):110639.
PMID: 35385730
To investigate changes in the tumor microenvironment (TME) during lung cancer progression, we interrogate tumors from two chest computed tomography (CT)-defined groups. Pure non-solid (pNS) CT density nodules contain preinvasive/minimally...
18.
Yoo S, Sinha A, Yang D, Altorki N, Tandon R, Wang W, et al.
Nat Commun
. 2022 Mar;
13(1):1592.
PMID: 35332150
Here we focus on the molecular characterization of clinically significant histological subtypes of early-stage lung adenocarcinoma (esLUAD), which is the most common histological subtype of lung cancer. Within lung adenocarcinoma,...
19.
Wennerberg E, Mukherjee S, Spada S, Hung C, Agrusa C, Chen C, et al.
Sci Transl Med
. 2022 Mar;
14(636):eabe8195.
PMID: 35294260
Most patients with non-small cell lung cancer (NSCLC) do not achieve durable clinical responses from immune checkpoint inhibitors, suggesting the existence of additional resistance mechanisms. Nicotinamide adenine dinucleotide (NAD)-induced cell...
20.
Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, et al.
Cell Rep Med
. 2022 Mar;
3(2):100522.
PMID: 35233546
The molecular mechanisms underlying the clinical manifestations of coronavirus disease 2019 (COVID-19), and what distinguishes them from common seasonal influenza virus and other lung injury states such as acute respiratory...