Alabbas Alkhatib
Overview
Explore the profile of Alabbas Alkhatib including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
134
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0
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Recent Articles
1.
Vadakumchery A, Faraidun H, El Ayoubi O, Outaleb I, Schmid V, Abdelrasoul H, et al.
Front Immunol
. 2022 Apr;
13:842340.
PMID: 35371049
The generation, differentiation, survival and activation of B cells are coordinated by signals emerging from the B cell antigen receptor (BCR) or its precursor, the pre-BCR. The adaptor protein SLP65...
2.
Minici C, Gounari M, Ubelhart R, Scarfo L, Minden M, Schneider D, et al.
Nat Commun
. 2017 Jun;
8:15746.
PMID: 28598442
Cell-autonomous B-cell receptor (BcR)-mediated signalling is a hallmark feature of the neoplastic B lymphocytes in chronic lymphocytic leukaemia (CLL). Here we elucidate the structural basis of autonomous activation of CLL...
3.
Schneider D, Minden M, Alkhatib A, Setz C, van Bergen C, Benkisser-Petersen M, et al.
Blood
. 2015 Mar;
125(21):3287-96.
PMID: 25784678
B-cell antigen receptor (BCR) expression is a key feature of most B-cell lymphomas, but the mechanisms of BCR signal induction and the involvement of autoantigen recognition remain unclear. In follicular...
4.
Alkhatib A, Werner M, Hug E, Herzog S, Eschbach C, Faraidun H, et al.
J Exp Med
. 2012 Feb;
209(2):395-406.
PMID: 22291095
Somatic rearrangement of immunoglobulin (Ig) genes is a key step during B cell development. Using pro-B cells lacking the phosphatase Pten (phosphatase and tensin homolog), which negatively regulates phosphoinositide-3-kinase (PI3K)...