Alaa A Osman
Overview
Explore the profile of Alaa A Osman including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
5
Citations
77
Followers
0
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Recent Articles
1.
Fouad M, Osman A, Abdelhamid N, Rashad M, Nabawy A, El Kerdawy A
BMC Chem
. 2024 Feb;
18(1):29.
PMID: 38347617
VEGFR2 and FAK signaling pathways are interconnected and have synergistic effects on tumor angiogenesis, growth, and metastasis. Thus, instead of the conventional targeting of each of these proteins individually with...
2.
Abdel-Mohsen H, Omar M, Kutkat O, El Kerdawy A, Osman A, GabAllah M, et al.
J Mol Struct
. 2022 Dec;
1276:134690.
PMID: 36465802
In the current investigation, two novel series of (tetrahydro)thioquinazoline--arylacetamides and (tetrahydro)thioquinazoline--arylacetohydrazides were designed, synthesized and investigated for their antiviral activity against SARS-CoV-2. The thioquinazoline--arylacetamide as well as the tetrahydrothioquinazoline--arylacetohydrazides and...
3.
Saied E, El-Maradny Y, Osman A, Darwish A, Abo Nahas H, Niedbala G, et al.
Pharmaceutics
. 2021 Nov;
13(11).
PMID: 34834174
In 2019, the world suffered from the emergence of COVID-19 infection, one of the most difficult pandemics in recent history. Millions of confirmed deaths from this pandemic have been reported...
4.
El Azab I, Saied E, Osman A, Mehana A, Saad H, Elkanzi N
Future Med Chem
. 2021 Aug;
13(20):1743-1766.
PMID: 34427113
Thiazole-substituted pyrazole is an important structural feature of many bioactive compounds, including antiviral, antitubercular, analgesic and anticancer agents. Herein we describe an efficient and facile approach for the synthesis of...
5.
El Kerdawy A, Osman A, Zaater M
J Mol Model
. 2019 May;
25(6):171.
PMID: 31129879
Considering the emerging importance of glycogen synthase kinase 3 beta (GSK-3β) inhibitors in treatment of Alzheimer's disease, multi-protein structure receptor-based pharmacophore modeling was adopted to generate a 3D pharmacophore model...