Akiyoshi Komuro
Overview
Explore the profile of Akiyoshi Komuro including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
894
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Recent Articles
1.
Honda M, Inoue R, Nishiyama K, Ueda T, Komuro A, Amano H, et al.
J Cell Physiol
. 2024 Sep;
239(12):e31436.
PMID: 39286968
During skeletal muscle adaptation to physiological or pathophysiological signals, contractile apparatus and mitochondrial function are coordinated to alter muscle fiber type. Although recent studies have identified various factors involved in...
2.
Dash S, Ueda T, Komuro A, Honda M, Sugisawa R, Okada H
Cell Death Dis
. 2024 May;
15(5):384.
PMID: 38821944
No abstract available.
3.
Dash S, Ueda T, Komuro A, Honda M, Sugisawa R, Okada H
Cell Death Dis
. 2024 Feb;
15(2):131.
PMID: 38346958
Pancreatic ductal adenocarcinoma (PDAC) is considered one of the most lethal forms of cancer. Although in the last decade, an increase in 5-year patient survival has been observed, the mortality...
4.
Dash S, Ueda T, Komuro A, Amano H, Honda M, Kawazu M, et al.
Mol Cancer Res
. 2023 Feb;
21(5):444-457.
PMID: 36757299
Implications: Our study revealed the key pathways involved in gemcitabine resistance in PDAC, thus providing potential therapeutic strategies.
5.
KDM4B promotes acute myeloid leukemia associated with AML1-ETO by regulating chromatin accessibility
Ueda T, Kanai A, Komuro A, Amano H, Ota K, Honda M, et al.
FASEB Bioadv
. 2021 Dec;
3(12):1020-1033.
PMID: 34938963
Epigenetic alterations of chromatin structure affect chromatin accessibility and collaborate with genetic alterations in the development of cancer. Lysine demethylase 4B (KDM4B) has been identified as a JmjC domain-containing epigenetic...
6.
Tanabe R, Miyazono K, Todo T, Saito N, Iwata C, Komuro A, et al.
Mol Oncol
. 2021 Jul;
16(1):269-288.
PMID: 34214250
Glioma-initiating cells (GICs), a major source of glioblastoma recurrence, are characterized by the expression of neural stem cell markers and the ability to grow by forming nonadherent spheres under serum-free...
7.
Oka N, Komuro A, Amano H, Dash S, Honda M, Ota K, et al.
Pharmacol Res Perspect
. 2020 Jul;
8(4):e00632.
PMID: 32725721
Osteosarcoma (OS) is the most common malignant bone tumor and a leading cause of cancer-related deaths in children and adolescents. Current standard treatments for OS are a combination of preoperative...
8.
Ota K, Komuro A, Amano H, Kanai A, Ge K, Ueda T, et al.
Sci Rep
. 2019 Jul;
9(1):10036.
PMID: 31296899
Obesity increases the risk of metabolic disorders like diabetes mellitus and dyslipidemia. However, how metabolic status is sensed and regulates cellular behavior is unclear. Utx is an H3K27 demethylase that...
9.
Komuro A, Raja E, Iwata C, Soda M, Isogaya K, Yuki K, et al.
Int J Cancer
. 2017 Dec;
142(8):1627-1639.
PMID: 29193056
Glioblastoma is one of the most malignant forms of cancer, for which no effective targeted therapy has been found. Although The Cancer Genome Atlas has provided a list of fusion...
10.
Ota K, Tong K, Goto K, Tomida S, Komuro A, Wang Z, et al.
PLoS One
. 2017 Mar;
12(3):e0173713.
PMID: 28319137
Understanding the molecular mechanisms that drive adipogenesis is important in developing new treatments for obesity and diabetes. Epigenetic regulations determine the capacity of adipogenesis. In this study, we examined the...