Akiyoshi Hirayama
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Explore the profile of Akiyoshi Hirayama including associated specialties, affiliations and a list of published articles.
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129
Citations
3515
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Recent Articles
1.
Takami N, Okazaki M, Ozeki T, Imaizumi T, Nishibori N, Kurasawa S, et al.
Kidney360
. 2024 Dec;
PMID: 39652407
Background: Protein-energy wasting, characterized by disordered body protein catabolism resulting from metabolic and nutritional derangements, is associated with adverse clinical outcomes in patients undergoing hemodialysis. Extended-hours hemodialysis (≥6 h per...
2.
Pan Y, Hatano A, Ohno S, Morita K, Kokaji T, Bai Y, et al.
NPJ Syst Biol Appl
. 2024 Sep;
10(1):107.
PMID: 39349490
Hepatic glucose metabolism serves dual purposes: maintaining glucose homeostasis and converting glucose into energy sources; however, the underlying mechanisms are unclear. We quantitatively measured liver metabolites, gene expression, and phosphorylated...
3.
Grant E, Parrish A, Boudaud M, Hunewald O, Hirayama A, Ollert M, et al.
Microbiome
. 2024 Sep;
12(1):179.
PMID: 39307855
Background: Dietary fibers can alter microbial metabolic output in support of healthy immune function; however, the impact of distinct fiber sources and immunomodulatory effects beyond short-chain fatty acid production are...
4.
Maruyama Y, Fujii N, Kawamata R, Yamada K, Ichiba Y, Kakizawa Y, et al.
Clin Chim Acta
. 2024 Sep;
565:119965.
PMID: 39284378
Background And Aims: Collecting clinical samples without inconveniencing participants is desirable. The profile of metabolites in mouth-rinsed water is similar to that in saliva. However, the intra- and inter-day variations...
5.
Nakasuka F, Hirayama A, Makinoshima H, Yano S, Soga T, Tabata S
FEBS Open Bio
. 2024 Jul;
14(9):1570-1583.
PMID: 39030877
Epithelial-to-mesenchymal transition (EMT) contributes to the poor prognosis of patients with cancer by promoting distant metastasis and anti-cancer drug resistance. Several distinct metabolic alterations have been identified as key EMT...
6.
Yoshida Y, Hirayama A, Arakawa K
Proc Jpn Acad Ser B Phys Biol Sci
. 2024 Jun;
100(7):414-428.
PMID: 38839369
Tardigrades are microscopic animals that are renowned for their capabilities of tolerating near-complete desiccation by entering an ametabolic state called anhydrobiosis. However, many species also show high tolerance against radiation...
7.
Ishibashi Y, Harada S, Eitaki Y, Kurihara A, Kato S, Kuwabara K, et al.
Environ Health Prev Med
. 2024 Mar;
29:22.
PMID: 38556356
Background: The application of metabolomics-based profiles in environmental epidemiological studies is a promising approach to refine the process of health risk assessment. We aimed to identify potential metabolomics-based profiles in...
8.
Fukuda H, Arai K, Mizuno H, Nishito Y, Motoi N, Arai Y, et al.
Cancer Sci
. 2024 Mar;
115(6):1763-1777.
PMID: 38527308
Overcoming resistance to immune checkpoint inhibitors is an important issue in patients with non-small-cell lung cancer (NSCLC). Transcriptome analysis shows that adenocarcinoma can be divided into three molecular subtypes: terminal...
9.
Bai Y, Morita K, Kokaji T, Hatano A, Ohno S, Egami R, et al.
iScience
. 2024 Mar;
27(3):109121.
PMID: 38524370
Dysregulation of liver metabolism associated with obesity during feeding and fasting leads to the breakdown of metabolic homeostasis. However, the underlying mechanism remains unknown. Here, we measured multi-omics data in...
10.
Matsuzaki J, Kurokawa S, Iwamoto C, Miyaho K, Takamiya A, Ishii C, et al.
Gut Pathog
. 2024 Feb;
16(1):8.
PMID: 38336806
Background: The impact of the gut microbiota on neuropsychiatric disorders has gained much attention in recent years; however, comprehensive data on the relationship between the gut microbiome and its metabolites...