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Akira Takasawa

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Articles 78
Citations 771
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Recent Articles
1.
Nakamura J, Yamamoto T, Takabatake Y, Namba-Hamano T, Takahashi A, Matsuda J, et al.
JCI Insight . 2024 Dec; 10(3). PMID: 39699959
With the aging of society, the incidence of chronic kidney disease (CKD), a common cause of death, has been increasing. Transcription factor EB (TFEB), the master transcriptional regulator of the...
2.
Nakahashi N, Emori M, Takada K, Murahashi Y, Shimizu J, Murase K, et al.
Hum Cell . 2024 Dec; 38(1):25. PMID: 39625530
Myxofibrosarcoma (MFS) is one of the most common soft-tissue sarcomas in elderly patients. Owing to the limited efficacy of chemotherapy and radiotherapy, complete resection is the only available curative treatment....
3.
Matsumoto K, Goto M, Kamikokura Y, Takasawa K, Kobayashi N, Aoyama T, et al.
Med Mol Morphol . 2024 Aug; 57(4):326-332. PMID: 39141108
Invasive fungal infections including invasive pulmonary aspergillosis (IPA) generally have a poor prognosis, because the fungi spread throughout various organs. Therefore, it is important to accurately identify the fungal species...
4.
Yamamoto S, Ogasawara N, Sudo-Yokoyama Y, Sato S, Takata N, Yokota N, et al.
Sci Rep . 2024 Jul; 14(1):15181. PMID: 38956295
Human norovirus (HuNoV) is an enteric infectious pathogen belonging to the Caliciviridae family that causes occasional epidemics. Circulating alcohol-tolerant viral particles that are readily transmitted via food-borne routes significantly contribute...
5.
Magara K, Takasawa A, Takasawa K, Aoyama T, Ota M, Kyuno D, et al.
Cancer Sci . 2024 Jun; 115(9):3153-3168. PMID: 38943512
Recent studies have shown that transmembrane-type tight junction proteins are upregulated in various cancers compared with their levels in normal tissues and are involved in cancer progression, suggesting that they...
6.
Nakamori Y, Takasawa A, Takasawa K, Kyuno D, Ono Y, Magara K, et al.
Med Mol Morphol . 2024 May; 57(3):185-199. PMID: 38772955
Vitamin D is an essential molecule for cellular homeostasis, playing a critical role in cell fate decisions including cell proliferation, differentiation, and viability. Accumulating evidence has revealed that expression of...
7.
Aoki H, Takasawa A, Yamamoto E, Niinuma T, Yamano H, Harada T, et al.
BMC Gastroenterol . 2024 Mar; 24(1):91. PMID: 38429655
Background: Aberrant DNA methylation is prevalent in colorectal serrated lesions. We previously reported that the CpG island of SMOC1 is frequently methylated in traditional serrated adenomas (TSAs) and colorectal cancers...
8.
Kyuno D, Tateno M, Ono Y, Magara K, Takasawa K, Takasawa A, et al.
Heliyon . 2023 Oct; 9(10):e20564. PMID: 37842587
Background: Cardiomyopathy is a leading cause of sudden out-of-hospital death after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccination. Such unexpected COVID-19-related cardiomyopathies are...
9.
Emori M, Tsuchie H, Takashima H, Teramoto A, Murahashi Y, Imura Y, et al.
Skeletal Radiol . 2023 Sep; 53(4):657-664. PMID: 37755491
Background: We investigated whether non-enhancement MRI features, including measurement of the heterogeneity of the tumor with MR T2 imaging by calculating coefficient of variation (CV) values, were associated with the...
10.
Sekiguchi S, Yorozu A, Okazaki F, Niinuma T, Takasawa A, Yamamoto E, et al.
Cancers (Basel) . 2023 Sep; 15(17). PMID: 37686580
We previously showed that upregulation of adipocyte enhancer-binding protein 1 () in vascular endothelial cells promotes tumor angiogenesis. In the present study, we aimed to clarify the role of stromal...