Akiko Osada
Overview
Explore the profile of Akiko Osada including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
9
Citations
124
Followers
0
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Recent Articles
1.
Oguchi K, Araki H, Tsuji S, Nakamura M, Miura A, Funabashi K, et al.
Cancer Sci
. 2022 Oct;
114(2):654-664.
PMID: 36282234
Genetic alterations in human epidermal growth factor receptor type 2 (HER2)/epidermal growth factor receptor (EGFR) are commonly associated with breast and lung cancers and glioblastomas. Cancers with avian erythroblastosis oncogene...
2.
Yokogawa T, Yano W, Tsukioka S, Osada A, Wakasa T, Ueno H, et al.
Cancer Sci
. 2020 Nov;
112(1):422-432.
PMID: 33140501
Deficiency in DNA repair proteins confers susceptibility to DNA damage, making cancer cells vulnerable to various cancer chemotherapies. 5-Fluorouracil (5-FU) is an anticancer nucleoside analog that both inhibits thymidylate synthase...
3.
Sakamoto K, Yokogawa T, Ueno H, Oguchi K, Kazuno H, Ishida K, et al.
Int J Oncol
. 2015 Apr;
46(6):2327-34.
PMID: 25901475
Trifluridine (FTD) and 2'-deoxy-5-fluorouridine (FdUrd), a derivative of 5-fluorouracil (5-FU), are antitumor agents that inhibit thymidylate synthase activity and their nucleotides are incorporated into DNA. However, it is evident that...
4.
Tanaka N, Sakamoto K, Okabe H, Fujioka A, Yamamura K, Nakagawa F, et al.
Oncol Rep
. 2014 Sep;
32(6):2319-26.
PMID: 25230742
TAS-102 is a novel oral nucleoside antitumor agent containing trifluridine (FTD) and tipiracil hydrochloride (TPI). The compound improves overall survival of colorectal cancer (CRC) patients who are insensitive to standard...
5.
Sako Y, Ichikawa S, Osada A, Matsuda A
Bioorg Med Chem
. 2010 Oct;
18(22):7878-89.
PMID: 20943405
The structure-activity relationship (SAR) of 5-substituted pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione derivatives 5 was investigated for their potential as Chk1 inhibitors for possible chemo- and radio-potentiators in anticancer chemotherapies. In silico virtual screening helped...
6.
Sekiguchi H, Muranaka K, Osada A, Ichikawa S, Matsuda A
Bioorg Med Chem
. 2010 Jul;
18(15):5732-7.
PMID: 20609590
The PU-H58-dimers 13a-15b were efficiently synthesized and their biological properties were evaluated. The copper-catalyzed alkyne azide coupling was effective in simultaneously linking three components via a triazole formation to afford...
7.
Sugiura K, Sugiura M, Hayakawa R, Kato Y, Sakamoto N, Osada A, et al.
Int J Dermatol
. 2004 Jun;
43(6):451-3.
PMID: 15186230
No abstract available.
8.
Sugiura K, Sugiura M, Hayakawa R, Kato Y, Shamoto M, Mizoguchi Y, et al.
Dermatology
. 2004 Apr;
208(2):183-4.
PMID: 15057021
No abstract available.
9.
Sugiura K, Shamoto M, Sakamoto N, Shinzato M, Osada A, Sugiura M, et al.
Dermatology
. 2003 Apr;
206(3):222-4.
PMID: 12673079
Background: Generally, Langerhans cells deliver antigen information from the skin to the draining lymph nodes via lymph vessels. Methods: By immunohistopathology, we investigated the delivery route of Langerhans cells in...