Ajit Wilson
Overview
Explore the profile of Ajit Wilson including associated specialties, affiliations and a list of published articles.
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20
Citations
359
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Recent Articles
11.
Sindhu S, Thomas R, Kochumon S, Wilson A, Abu-Farha M, Bennakhi A, et al.
Cells
. 2019 Nov;
8(11).
PMID: 31718015
Interferon regulatory factor (IRF)-5 is known to be involved in M1 macrophage polarization, however, changes in the adipose expression of IRF5 in obesity and their relationship with the local expression...
12.
Sindhu S, Kochumon S, Shenouda S, Wilson A, Al-Mulla F, Ahmad R
Int J Mol Sci
. 2019 Sep;
20(18).
PMID: 31546972
Chronic low-grade inflammation, also known as metabolic inflammation, is a hallmark of obesity and parallels with the presence of elevated circulatory levels of free fatty acids and inflammatory cytokines/chemokines. CCL4/MIP-1β...
13.
Hasan A, Akhter N, Al-Roub A, Thomas R, Kochumon S, Wilson A, et al.
Int J Mol Sci
. 2019 Aug;
20(17).
PMID: 31443599
Elevated levels of IL-8 (CXCL8) in obesity have been linked with insulin resistance and type 2 diabetes (T2D). The mechanisms that lead to the profound production of IL-8 in obesity...
14.
Akhter N, Madhoun A, Arefanian H, Wilson A, Kochumon S, Thomas R, et al.
Cell Physiol Biochem
. 2019 Jun;
53(1):1-18.
PMID: 31162913
Background/aims: Innate immune toll-like receptors (TLRs) are emerging as nutrient sensors. Oxidative stress in the adipose tissue in obesity acts as a critical early trigger of altered pathophysiology. TLR2/TLR4 adipose...
15.
Ahmad R, Akhter N, Al-Roub A, Kochumon S, Wilson A, Thomas R, et al.
Cell Physiol Biochem
. 2019 Mar;
52(2):212-224.
PMID: 30816669
Background/aims: MIP-1α (macrophage inflammatory protein 1α)/CCL3 chemokine is associated with the adipose tissue inflammation in obesity. Both MIP-1α and free fatty acids are elevated in obesity/T2D. We asked if free...
16.
Akhter N, Hasan A, Shenouda S, Wilson A, Kochumon S, Ali S, et al.
J Diabetes Metab Disord
. 2018 Oct;
17(1):77-84.
PMID: 30288388
Background: Obese human and mice were reported to have higher circularity endotoxin (LPS) levels as compared to their lean counter parts. The current study was aimed to reveal the molecular...
17.
Kochumon S, Wilson A, Chandy B, Shenouda S, Tuomilehto J, Sindhu S, et al.
Cell Physiol Biochem
. 2018 Apr;
46(3):953-964.
PMID: 29669317
Background/aims: Obesity is associated with adipose tissue inflammation which plays a key role in the development of insulin resistance and type 2 diabetes (T2D). Saturated free fatty acids (SFAs) levels...
18.
Sindhu S, Akhter N, Kochumon S, Thomas R, Wilson A, Shenouda S, et al.
Cell Physiol Biochem
. 2018 Feb;
45(2):572-590.
PMID: 29428931
Background/aims: Metabolic diseases such as obesity and type-2 diabetes (T2D) are known to be associated with chronic low-grade inflammation called metabolic inflammation together with an oxidative stress milieu found in...
19.
Sindhu S, Akhter N, Arefanian H, Al-Roub A, Ali S, Wilson A, et al.
J Diabetes Metab Disord
. 2017 Apr;
16:15.
PMID: 28396851
Background: Fractalkine (CX3CL1) is involved in the development of numerous inflammatory conditions including metabolic diseases. However, changes in the circulatory fractalkine levels in type-2 diabetes (T2D) and their relationship with...
20.
Sindhu S, Akhter N, Shenouda S, Wilson A, Ahmad R
BMC Immunol
. 2016 Sep;
17(1):33.
PMID: 27671862
Background: Fetuin-A/AHSH is a novel hepatokine that acts as a vascular calcification inhibitor and as an endogenous TLR-4 ligand. Fetuin-A may act as a positive or negative acute phase protein...