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Ajay K Malik

Explore the profile of Ajay K Malik including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 834
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Recent Articles
1.
Malik A, Khaldoyanidi S, Auci D, Miller S, Ahlem C, Reading C, et al.
PLoS One . 2010 Nov; 5(10):e13566. PMID: 21042414
5-Androstene-3β,7β,17β-triol (β-AET), an active metabolite of dehydroepiandrosterone (DHEA), reversed glucocorticoid (GC)-induced suppression of IL-6, IL-8 and osteoprotegerin production by human osteoblast-like MG-63 cells and promoted osteoblast differentiation of human mesenchymal...
2.
Shojaei F, Wu X, Malik A, Zhong C, Baldwin M, Schanz S, et al.
Nat Biotechnol . 2007 Aug; 25(8):911-20. PMID: 17664940
Vascular endothelial growth factor (VEGF) is an essential regulator of normal and abnormal blood vessel growth. A monoclonal antibody (mAb) that targets VEGF suppresses tumor growth in murine cancer models...
3.
Liang W, Wu X, Peale F, Lee C, Meng Y, Gutierrez J, et al.
J Biol Chem . 2005 Nov; 281(2):951-61. PMID: 16278208
To fully assess the role of VEGF-A in tumor angiogenesis, antibodies that can block all sources of vascular endothelial growth factor (VEGF) are desired. Selectively targeting tumor-derived VEGF overlooks the...
4.
Malik A, Baldwin M, Peale F, Fuh G, Liang W, Lowman H, et al.
Blood . 2005 Sep; 107(2):550-7. PMID: 16189273
Vascular endothelial growth factor-A (VEGF-A) and its 2 transmembrane tyrosine-kinase receptors, VEGFR-1 and VEGFR-2, constitute a ligand-receptor signaling system that is crucial for developmental angiogenesis. VEGF-B and placental growth factor...
5.
Krebsbach P, Zhang K, Malik A, Kurachi K
J Gene Med . 2003 Jan; 5(1):11-7. PMID: 12516047
Background: Hemophilia B is an X-linked bleeding disorder that results from a deficiency in functional coagulation factor IX (hFIX). In patients lacking FIX, the intrinsic coagulation pathway is disrupted leading...
6.
Gerber H, Malik A, Solar G, Sherman D, Liang X, Meng G, et al.
Nature . 2002 Jun; 417(6892):954-8. PMID: 12087404
Vascular endothelial growth factor (VEGF) is a principal regulator of blood vessel formation and haematopoiesis, but the mechanisms by which VEGF differentially regulates these processes have been elusive. Here we...