Ajaikumar B Kunnumakkara
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Explore the profile of Ajaikumar B Kunnumakkara including associated specialties, affiliations and a list of published articles.
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187
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11664
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Recent Articles
11.
Aswathy M, Parama D, Hegde M, Dr S, Lankalapalli R, Radhakrishnan K, et al.
ACS Omega
. 2024 Jun;
9(23):24252-24267.
PMID: 38882137
Artonin E (AA2) and artobiloxanthone (AA3) were extracted and purified from the acetone extract of the stem bark of (Parkinson) Fosberg. Preliminary investigations of both candidates revealed promising cytotoxic effects...
12.
Parama D, BharathwajChetty B, Jayaprakash S, Lee E, Khatoon E, AlQahtani M, et al.
Life Sci
. 2024 Jun;
351:122785.
PMID: 38851420
Lung cancer stands as one of the most lethal diseases and is the foremost cause of cancer-related mortalities worldwide. The pathophysiology of lung cancer is multifaceted, and it includes multiple...
13.
Sajeev A, Sailo B, Unnikrishnan J, Talukdar A, AlQahtani M, Abbas M, et al.
Cancer Lett
. 2024 Jun;
597:217019.
PMID: 38849013
Despite considerable progress in cancer treatment options, resistance to chemotherapeutic drugs remains a significant challenge. This review focuses on Berberine (BBR), an isoquinoline alkaloid found in various medicinal plants, which...
14.
Hegde M, Girisa S, Aswani B, AlQahtani M, Abbas M, Sethi G, et al.
Life Sci
. 2024 Jun;
351:122786.
PMID: 38848944
Gangliosides represent glycolipids containing sialic acid residues, present on the cell membrane with glycan residues exposed to the extracellular matrix (ECM), while the ceramides are anchored within the membrane. These...
15.
Kumar A, BharathwajChetty B, Manickasamy M, Unnikrishnan J, AlQahtani M, Abbas M, et al.
Pharmacol Res
. 2024 Apr;
203:107167.
PMID: 38599470
Cancer has become a burgeoning global healthcare concern marked by its exponential growth and significant economic ramifications. Though advancements in the treatment modalities have increased the overall survival and quality...
16.
BharathwajChetty B, Sajeev A, Vishwa R, Aswani B, AlQahtani M, Abbas M, et al.
Cancer Metastasis Rev
. 2024 Mar;
43(1):321-362.
PMID: 38517618
Recent advances have brought forth the complex interplay between tumor cell plasticity and its consequential impact on drug resistance and tumor recurrence, both of which are critical determinants of neoplastic...
17.
Saha P, Hegde M, Chakraborty K, Singha A, Mukerjee N, Ghosh D, et al.
J Cell Mol Med
. 2024 Mar;
28(7):e18150.
PMID: 38494866
The anti-apoptotic proteins, Bcl-2 and Survivin, are consistently overexpressed in numerous human malignancies, notably in colorectal cancer. 2,4-Di-tert-butylphenol (2,4-DTBP) is a naturally occurring phenolic compound known for its diverse biological...
18.
Siddique H, Kunnumakkara A
Cancer Metastasis Rev
. 2024 Mar;
43(1):3.
PMID: 38443717
No abstract available.
19.
Vishwa R, BharathwajChetty B, Girisa S, Aswani B, AlQahtani M, Abbas M, et al.
Cancer Metastasis Rev
. 2024 Mar;
43(1):293-319.
PMID: 38438800
Metabolic reprogramming, a hallmark of cancer, allows cancer cells to adapt to their specific energy needs. The Warburg effect benefits cancer cells in both hypoxic and normoxic conditions and is...
20.
Manickasamy M, Jayaprakash S, Girisa S, Kumar A, Lam H, Okina E, et al.
Discov Oncol
. 2024 Feb;
15(1):41.
PMID: 38372868
Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally, causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to GLOBOCAN...