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Aiyun Yuan

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Articles 5
Citations 22
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Recent Articles
1.
Ren R, Liu Y, Liu P, Zhao J, Hou M, Li S, et al.
BMC Med Genomics . 2024 Dec; 17(1):290. PMID: 39696517
Background: Kleefstra syndrome spectrum (KLEFS) is an autosomal dominant disorder that can lead to intellectual disability and autism spectrum disorders. KLEFS encompasses Kleefstra syndrome-1 (KLEFS1) and Kleefstra syndrome-2 (KLEFS2), with...
2.
Zhou Z, Zheng X, Zhao J, Yuan A, Lv Z, Shao G, et al.
Oncogene . 2024 Apr; 43(23):1769-1778. PMID: 38632437
Pyruvate kinase M2 (PKM2) is a central metabolic enzyme driving the Warburg effect in tumor growth. Previous investigations have demonstrated that PKM2 is subject to O-linked β-N-acetylglucosamine (O-GlcNAc) modification, which...
3.
Yuan A, Tang X, Li J
Front Endocrinol (Lausanne) . 2021 Feb; 11:621888. PMID: 33597927
The centrosome apparatus is vital for spindle assembly and chromosome segregation during mitotic divisions. Its replication, disjunction and separation have to be fine-tuned in space and time. A multitude of...
4.
Liu Q, Wang H, Zhao J, Liu Z, Sun D, Yuan A, et al.
Int J Dev Neurosci . 2020 Apr; 80(6):455-463. PMID: 32233090
Joubert syndrome (JS) is a rare clinically and genetically heterogeneous disease. Using whole or targeted exome sequencing, we identified four novel compound heterozygous mutations in chromosome 5 open reading frame...
5.
Yuan A, Li J, Liu P, Chen Z, Hou M, Wang J, et al.
Inflammation . 2014 Aug; 38(2):728-35. PMID: 25081498
Interleukin-6 (IL-6), as one of pro-inflammatory cytokines, plays a key role in Enterovirus 71 (EV71) encephalitis. We investigated the association of IL-6-572C/G polymorphism and serum or cerebrospinal fluid (CSF) IL-6...