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Aivar Liiv

Explore the profile of Aivar Liiv including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 502
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Recent Articles
1.
Reier K, Liiv A, Remme J
Microbiol Resour Announc . 2024 Apr; 13(6):e0004224. PMID: 38651856
The expression level of individual proteins varies markedly during the progression of the growth phase in bacteria. A set of proteins was quantified in total proteome during 14 days of...
2.
Ero R, Leppik M, Reier K, Liiv A, Remme J
Nucleic Acids Res . 2024 Mar; 52(11):6614-6628. PMID: 38554109
Ribosomal RNA modifications are introduced by specific enzymes during ribosome assembly in bacteria. Deletion of individual modification enzymes has a minor effect on bacterial growth, ribosome biogenesis, and translation, which...
3.
Reier K, Liiv A, Remme J
Int J Mol Sci . 2023 Feb; 24(4). PMID: 36834540
Bacterial ribosomes contain over 50 ribosome core proteins (r-proteins). Tens of non-ribosomal proteins bind to ribosomes to promote various steps of translation or suppress protein synthesis during ribosome hibernation. This...
4.
Reier K, Lahtvee P, Liiv A, Remme J
mBio . 2022 Aug; 13(5):e0187322. PMID: 35980033
Bacterial ribosomes are composed of three rRNA and over 50 ribosomal protein (r-protein) molecules. r-proteins are essential for ribosome assembly and structural stability and also participate in almost all ribosome...
5.
Liljeruhm J, Leppik M, Bao L, Truu T, Calvo-Noriega M, Freyer N, et al.
RNA . 2022 Mar; 28(6):796-807. PMID: 35260421
rRNAs are post-transcriptionally modified at 36 positions but their modification enzymes are dispensable individually for growth, bringing into question their significance. However, a major growth defect was reported for deletion...
6.
Datta M, Pillai M, Modak M, Liiv A, Khaja F, Hussain T, et al.
Mol Microbiol . 2020 Dec; 115(6):1292-1308. PMID: 33368752
The ribosomal protein uS12 is conserved across all domains of life. Recently, a heterozygous spontaneous mutation in human uS12 (corresponding to R49K mutation immediately downstream of the universally conserved PNSA...
7.
Lilleorg S, Reier K, Volonkin P, Remme J, Liiv A
Sci Rep . 2020 Jul; 10(1):11682. PMID: 32669635
Ribosomes are essential macromolecular complexes conducting protein biosynthesis in all domains of life. Cells can have heterogeneous ribosomes, i.e. ribosomes with various ribosomal RNA and ribosomal protein (r-protein) composition. However,...
8.
Lilleorg S, Reier K, Pulk A, Liiv A, Tammsalu T, Peil L, et al.
Biochimie . 2018 Oct; 156:169-180. PMID: 30359641
Ribosomes consist of many small proteins and few large RNA molecules. Both components are necessary for ribosome functioning during translation. According to widely accepted view, bacterial ribosomes contain always the...
9.
Leppik M, Liiv A, Remme J
Nucleic Acids Res . 2017 Mar; 45(10):6098-6108. PMID: 28334881
Pseudouridine is the most common modified nucleoside in RNA, which is found in stable RNA species and in eukaryotic mRNAs. Functional analysis of pseudouridine is complicated by marginal effect of...
10.
Lilleorg S, Reier K, Remme J, Liiv A
J Mol Biol . 2017 Feb; 429(7):1067-1080. PMID: 28238762
In bacteria, ribosomal subunits are connected via 12 intersubunit bridges involving RNA-RNA, RNA-protein, and protein-protein interactions. The only protein-protein bridge in the ribosome is ribosomal intersubunit bridge 1b (B1b), which...