Ainars Leonchiks
Overview
Explore the profile of Ainars Leonchiks including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
151
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Esposito G, Hunashal Y, Percipalle M, Fogolari F, Venit T, Leonchiks A, et al.
PLoS One
. 2024 May;
19(5):e0303839.
PMID: 38758765
The interaction between SARS-CoV-2 non-structural protein Nsp9 and the nanobody 2NSP90 was investigated by NMR spectroscopy using the paramagnetic perturbation methodology PENELOP (Paramagnetic Equilibrium vs Nonequilibrium magnetization Enhancement or LOss...
2.
Vogt A, Roesti E, Mohsen M, Leonchiks A, Vogel M, Bachmann M
Vaccines (Basel)
. 2021 Nov;
9(11).
PMID: 34835247
Type 2 Diabetes Mellitus (T2DM) is a chronic progressive disease, defined by insulin resistance and insufficient insulin secretion to maintain normoglycemia. Amyloidogenic aggregates are a hallmark of T2DM patients; they...
3.
Zrelovs N, Kurbatska V, Rudevica Z, Leonchiks A, Fridmanis D
Antibiotics (Basel)
. 2021 Feb;
10(2).
PMID: 33562778
Rapid spread of antibiotic resistance throughout the kingdom bacteria is inevitably bringing humanity towards the "post-antibiotic" era. The emergence of so-called "superbugs"-pathogen strains that develop resistance to multiple conventional antibiotics-is...
4.
Jaudzems K, Kurbatska V, Je Kabsons A, Bobrovs R, Rudevica Z, Leonchiks A
ACS Infect Dis
. 2019 Nov;
6(2):186-194.
PMID: 31724850
Because of its essential role as a bacterial virulence factor, enzyme sortase A (SrtA) has become an attractive target for the development of new antivirulence drugs against Gram-positive infections. Here...
5.
Raimondi M, Listro R, Cusimano M, La Franca M, Faddetta T, Gallo G, et al.
Bioorg Med Chem
. 2019 Feb;
27(5):721-728.
PMID: 30711310
New compounds able to counteract staphylococcal biofilm formation are needed. In this study we investigate the mechanism of action of pyrrolomycins, whose potential as antimicrobial agents has been demonstrated. We...
6.
Maggio B, Raffa D, Raimondi M, Cascioferro S, Plescia F, Schillaci D, et al.
Molecules
. 2016 Feb;
21(2):241.
PMID: 26907235
A FRET-based random screening assay was used to generate hit compounds as sortase A inhibitors that allowed us to identify ethyl 3-oxo-2-(2-phenylhydrazinylidene)butanoate as an example of a new class of...
7.
Zhulenkovs D, Rudevica Z, Jaudzems K, Turks M, Leonchiks A
Bioorg Med Chem
. 2014 Oct;
22(21):5988-6003.
PMID: 25282649
Gram-positive bacteria, in general, and staphylococci, in particular, are the widespread cause of nosocomial and community-acquired infections. The rapid evolvement of strains resistant to antibiotics currently in use is a...
8.
Urosev D, Ferrer-Navarro M, Pastorello I, Cartocci E, Costenaro L, Zhulenkovs D, et al.
BMC Struct Biol
. 2013 Oct;
13:19.
PMID: 24099525
Background: Increasing rates of antimicrobial resistance among uropathogens led, among other efforts, to the application of subtractive reverse vaccinology for the identification of antigens present in extraintestinal pathogenic E. coli...
9.
Pintacuda G, Moshref A, Leonchiks A, Sharipo A, Otting G
J Biomol NMR
. 2004 Jun;
29(3):351-61.
PMID: 15213433
A single free Cys sidechain in the N-terminal domain of the E. coli arginine repressor was covalently derivatized with S-cysteaminyl-EDTA for site-specific attachment of paramagnetic metal ions. The effects of...
10.
Liepinsh E, Leonchiks A, Sharipo A, Guignard L, Otting G
J Mol Biol
. 2003 Jan;
326(1):217-23.
PMID: 12547203
The R3H domain is a conserved sequence motif, identified in over 100 proteins, that is thought to be involved in polynucleotide-binding, including DNA, RNA and single-stranded DNA. In this work...