Aiko Teshima
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Explore the profile of Aiko Teshima including associated specialties, affiliations and a list of published articles.
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7
Citations
16
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Recent Articles
1.
Kodama T, Yokoyama A, Nishioka Y, Kawasaki R, Teshima A, Maeda A, et al.
Cytotechnology
. 2025 Feb;
77(2):69.
PMID: 40012927
Fermented plant product (FPP) is a dietary supplement made by fermentation and aging of a variety of plants, including fruits, vegetables, and grains. A previous study has shown that oral...
2.
Teklemichael A, Teshima A, Hirata A, Akimoto M, Taniguchi M, Khodakaramian G, et al.
Trop Med Health
. 2024 Jul;
52(1):47.
PMID: 38982547
Background: Natural products play a key role as potential sources of biologically active substances for the discovery of new drugs. This study aimed to identify secondary metabolites from actinomycete library...
3.
Takeuchi A, Hirata A, Teshima A, Ueki M, Satoh T, Matsuda K, et al.
Biosci Biotechnol Biochem
. 2022 Dec;
87(3):320-329.
PMID: 36496162
Kusaya, a traditional Japanese fermented fish product, is known for its high preservability, as it contains natural antibiotics derived from microorganisms, and therefore molds and yeasts do not colonize it...
4.
Ayoub A, Nishiura N, Teshima A, Elrefaiy M, Muslimin R, Do K, et al.
Future Med Chem
. 2022 Sep;
14(19):1349-1360.
PMID: 36073363
The 17-membered polyketide, lankacidin C, exhibits considerable antitumor activity as a microtubule stabilizer by binding to the paclitaxel binding site. Esterification of the C-7/C-13 hydroxyl in lankacidin C was performed ...
5.
Muslimin R, Nishiura N, Teshima A, Do K, Kodama T, Morita H, et al.
Bioorg Med Chem
. 2021 Dec;
53:116551.
PMID: 34883453
We investigated the importance of the δ-lactone ring (C1-C5) in lankacidin C using chemoenzymatic synthesis and computational prediction and assessing biological activity, including antitumor activity. Pyrroloquinoline quinone-dependent dehydrogenase (Orf23) in...
6.
Teshima A, Kondo H, Tanaka Y, Nindita Y, Misaki Y, Konaka Y, et al.
Biosci Biotechnol Biochem
. 2021 Feb;
85(1):115-125.
PMID: 33577670
To elucidate the gross lankamycin biosynthetic pathway including two cytochrome P450 monooxygenases, LkmK and LkmF, we constructed two double mutants of P450 genes in combination with glycosyltransferase genes, lkmL and...
7.
Teshima A, Hadae N, Tsuda N, Arakawa K
Biomolecules
. 2020 Aug;
10(9).
PMID: 32854353
7434AN4 produces two structurally unrelated polyketide antibiotics lankacidin and lankamycin, and their biosynthesis is tightly controlled by butenolide-type signaling molecules SRB1 and SRB2. SRBs are synthesized by SRB synthase SrrX,...
8.
Nindita Y, Cao Z, Fauzi A, Teshima A, Misaki Y, Muslimin R, et al.
Sci Rep
. 2019 Jul;
9(1):10973.
PMID: 31358803
Streptomyces rochei 7434AN4 produces two structurally unrelated polyketide antibiotics, lankacidin and lankamycin, and carries three linear plasmids, pSLA2-L (211 kb), -M (113 kb), and -S (18 kb), whose nucleotide sequences...