Aida Mohammadkhani
Overview
Explore the profile of Aida Mohammadkhani including associated specialties, affiliations and a list of published articles.
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9
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81
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Recent Articles
1.
Mohammadkhani A, Mitchell C, James M, Borgland S, Dayas C
Br J Pharmacol
. 2024 Sep;
181(22):4430-4449.
PMID: 39317446
The orexin (also known as hypocretin) system, consisting of neuropeptides orexin-A and orexin-B, was discovered over 25 years ago and was immediately identified as a central regulator of sleep and...
2.
Mohammadkhani A, Qiao M, Borgland S
J Neurosci
. 2024 Aug;
44(39).
PMID: 39187377
Dopamine (DA) neurons in the ventral tegmental area (VTA) respond to motivationally relevant cues, and circuit-specific signaling drives different aspects of motivated behavior. Orexin (ox; also known as hypocretin) and...
3.
Noble D, Mohammadkhani A, Qiao M, Borgland S
Eur J Neurosci
. 2023 Dec;
59(7):1460-1479.
PMID: 38155094
The orbitofrontal cortex (OFC) is a key node in the cortico-limbic-striatal circuitry that influences decision-making guided by the relative value of outcomes. Midbrain dopamine from either the ventral tegmental area...
4.
Becchi S, Hood J, Kendig M, Mohammadkhani A, Shipman M, Balleine B, et al.
Psychopharmacology (Berl)
. 2022 Oct;
239(11):3495-3506.
PMID: 36219247
Rationale: Attempts to lose weight often fail despite knowledge of the health risks associated with obesity and determined efforts. We previously showed that rodents fed an obesogenic diet displayed premature...
5.
Decker A, Brackeen M, Mohammadkhani A, Kormos C, Hesk D, Borgland S, et al.
ACS Chem Neurosci
. 2022 Mar;
13(7):1082-1095.
PMID: 35325532
Human trace amine-associated receptor subtype 1 (hTAAR1) is a G protein-coupled receptor that has therapeutic potential for multiple diseases, including schizophrenia, drug addiction, and Parkinson's disease (PD). Although several potent...
6.
Thomas C, Mohammadkhani A, Rana M, Qiao M, Baimel C, Borgland S
Neuropsychopharmacology
. 2021 Oct;
47(3):728-740.
PMID: 34663867
Reward and reinforcement processes are critical for survival and propagation of genes. While numerous brain systems underlie these processes, a cardinal role is ascribed to mesolimbic dopamine. However, ventral tegmental...
7.
Mohammadkhani A, Borgland S
J Neurosci Res
. 2020 Dec;
100(1):278-296.
PMID: 33352618
The brain's endogenous opioid and endocannabinoid systems are neuromodulatory of synaptic transmission, and play key roles in pain, memory, reward, and addiction. Recent clinical and pre-clinical evidence suggests that opioid...
8.
Mohammadkhani A, Fragale J, Pantazis C, Bowrey H, James M, Aston-Jones G
J Neurosci
. 2019 Oct;
39(49):9831-9840.
PMID: 31641055
Signaling at the orexin-1 receptor (OxR1) is important for motivated drug taking. Using a within-session behavioral economics (BE) procedure, we previously found that pharmacologic blockade of the OxR1 decreased motivation...
9.
Mohammadkhani A, James M, Pantazis C, Aston-Jones G
Brain Res
. 2019 Sep;
1731:146461.
PMID: 31526801
The orexin (hypocretin) system is multifaceted, and regulates sleep-wake cycles, nociception, endocrine function and reward-seeking behavior. We have established an important role for this system in motivation for drugs of...