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Ai Lin

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Articles 23
Citations 266
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Recent Articles
1.
Lin A, Liu Z, Yao J, Liu Y, Wan H
Pain Manag Nurs . 2024 Mar; 25(3):e192-e200. PMID: 38461044
Objectives: This study aimed to analyze the current status and influencing factors of pain catastrophizing in patients undergoing total knee replacement (TKR) and to provide a basis and reference for...
2.
Yu C, Liu Z, Zhao M, Liu Y, Zhang Y, Lin A, et al.
Psychol Res Behav Manag . 2023 Aug; 16:3333-3345. PMID: 37650114
Objective: To explore the influence of negative psychology and burnout in clinical nurses, and to analyse the mediating role between self-efficacy and emotional intelligence in emotion management. Methods: From January...
3.
Jonnakuti V, Ji P, Gao Y, Lin A, Chu Y, Elrod N, et al.
J Neurooncol . 2023 Jun; 163(3):623-634. PMID: 37389756
Purpose: Gliomas and their surrounding microenvironment constantly interact to promote tumorigenicity, yet the underlying posttranscriptional regulatory mechanisms that govern this interplay are poorly understood. Methods: Utilizing our established PAC-seq approach...
4.
Liu Y, Wu M, Xu S, Niu X, Liu W, Miao C, et al.
Cell Biosci . 2023 Mar; 13(1):67. PMID: 36998052
Background: The ubiquitin-proteasome and autophagy-lysosomal systems collaborate in regulating the levels of intracellular proteins. Dysregulation of protein homeostasis is a central feature of malignancy. The gene encoding 26S proteasome non-ATPase...
5.
de Prisco N, Ford C, Elrod N, Lee W, Tang L, Huang K, et al.
Sci Adv . 2023 Feb; 9(7):eade4814. PMID: 36800428
Alternative polyadenylation (APA) creates distinct transcripts from the same gene by cleaving the pre-mRNA at poly(A) sites that can lie within the 3' untranslated region (3'UTR), introns, or exons. Most...
6.
Xi Y, Lin Y, Guo W, Wang X, Zhao H, Miao C, et al.
Signal Transduct Target Ther . 2022 Feb; 7(1):53. PMID: 35210398
This study investigates aberrant DNA methylations as potential diagnosis and prognosis markers for esophageal squamous-cell carcinoma (ESCC), which if diagnosed at advanced stages has <30% five-year survival rate. Comparing genome-wide...
7.
LaForce G, Farr J, Liu J, Akesson C, Gumus E, Pinkard O, et al.
Neuron . 2022 Feb; 110(8):1340-1357.e7. PMID: 35139363
Tight regulation of mRNA isoform expression is essential for neuronal development, maintenance, and function; however, the repertoire of proteins that govern isoform composition and abundance remains incomplete. Here, we show...
8.
Lin A, Ji P, Niu X, Zhao X, Chen Y, Liu W, et al.
Cancer Res . 2021 Oct; 81(22):5638-5651. PMID: 34607841
The majority of human genes have multiple polyadenylation sites, which are differentially used through the process of alternative polyadenylation (APA). Dysregulation of APA contributes to numerous diseases, including cancer. However,...
9.
Liu W, Miao C, Zhang S, Liu Y, Niu X, Xi Y, et al.
Signal Transduct Target Ther . 2021 Aug; 6(1):322. PMID: 34462423
Radiotherapy remains the mainstay for treatment of various types of human cancer; however, the clinical efficacy is often limited by radioresistance, in which the underlying mechanism is largely unknown. Here,...
10.
Yalamanchili H, Elrod N, Jensen M, Ji P, Lin A, Wagner E, et al.
Methods Enzymol . 2021 Jun; 655:185-204. PMID: 34183121
An increasing number of investigations have established alternative polyadenylation (APA) as a key mechanism of gene regulation through altering the length of 3' untranslated region (UTR) and generating distinct mRNA...