Ai-Ping Lu
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Explore the profile of Ai-Ping Lu including associated specialties, affiliations and a list of published articles.
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171
Citations
2078
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Recent Articles
11.
Dai L, Xu J, Zhou W, Lu A, Ji G
J Integr Med
. 2022 Aug;
20(6):524-533.
PMID: 36031542
Objective: Appraisal of treatment outcomes in integrative medicine is a challenge due to a gap between the concepts of Western medicine (WM) disease and traditional Chinese medicine (TCM) syndrome. This...
12.
Tan Y, Yue S, Lu A, Zhang L, Ji G, Liu B, et al.
Phytomedicine
. 2022 Jun;
103:154208.
PMID: 35691078
Background: Nonalcoholic steatohepatitis (NASH) has been linked to inflammation induced by intestinal microbiota. Poria cocos polysaccharides (PCP) possesses anti-inflammation and immunomodulation functions; however, its preventive effects against NASH and potential...
13.
Wang N, Wang X, Xiong G, Yang Z, Lu A, Chen X, et al.
J Cheminform
. 2022 Apr;
14(1):23.
PMID: 35428354
Drug-drug interaction (DDI) often causes serious adverse reactions and thus results in inestimable economic and social loss. Currently, comprehensive DDI evaluation has become a major challenge in pharmaceutical research due...
14.
Wu Q, Yin C, Li Y, Cai J, Yang H, Huang Y, et al.
Front Pharmacol
. 2021 Dec;
12:769190.
PMID: 34938184
Sepsis is a systemic inflammatory reaction caused by various infectious or noninfectious factors, which can lead to shock, multiple organ dysfunction syndrome, and death. It is one of the common...
15.
Semi-automated workflow for molecular pair analysis and QSAR-assisted transformation space expansion
Yang Z, Fu L, Lu A, Liu S, Hou T, Cao D
J Cheminform
. 2021 Nov;
13(1):86.
PMID: 34774096
In the process of drug discovery, the optimization of lead compounds has always been a challenge faced by pharmaceutical chemists. Matched molecular pair analysis (MMPA), a promising tool to efficiently...
16.
Wang H, Liu C, Liu C, Wang Y, Han Z, Sun X, et al.
Zhongguo Dang Dai Er Ke Za Zhi
. 2021 Sep;
23(9):877-881.
PMID: 34535200
Objectives: To study the efficacy of Huaiqihuang granules as adjuvant therapy for bronchial asthma in children. Methods: A multicenter, prospective, and registered real-world study was performed for the children, aged...
17.
Wu C, Zhang X, Yang Z, Lu A, Hou T, Cao D
Brief Bioinform
. 2021 Aug;
22(6).
PMID: 34427296
Computational methods have become indispensable tools to accelerate the drug discovery process and alleviate the excessive dependence on time-consuming and labor-intensive experiments. Traditional feature-engineering approaches heavily rely on expert knowledge...
18.
Xiong G, Zhao Y, Liu L, Ma Z, Lu A, Cheng Y, et al.
J Med Chem
. 2021 May;
64(11):7544-7554.
PMID: 34008979
As one of the central tasks of modern medicinal chemistry, scaffold hopping is expected to lead to the discovery of structural novel biological active compounds and broaden the chemical space...
19.
Zhao Y, Wang X, Ma Z, Xiong G, Yang Z, Cheng Y, et al.
Brief Bioinform
. 2021 May;
22(6).
PMID: 33940596
The poly (ADP-ribose) polymerase-1 (PARP1) has been regarded as a vital target in recent years and PARP1 inhibitors can be used for ovarian and breast cancer therapies. However, it has...
20.
Wang K, Chen Y, Lu A, Du G, Qin X, Guan D, et al.
J Ethnopharmacol
. 2021 Mar;
274:114043.
PMID: 33753143
Ethnopharmacological Relevance: Compound Kushen Injection (CKI) is a widely used TCM formula for treatment of carcinomatous pain and tumors of digestive system including hepatocellular carcinoma (HCC). However, the potential mechanisms...