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Ahmed Edris

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Articles 12
Citations 128
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Recent Articles
1.
Edris A, Voorhies K, Lutz S, Iribarren C, Hall I, Wu A, et al.
ERJ Open Res . 2024 Jan; 10(1). PMID: 38196893
Background: Asthma exacerbations reflect disease severity, affect morbidity and mortality, and may lead to declining lung function. Inflammatory endotypes ( T2-high (eosinophilic)) may play a key role in asthma exacerbations....
2.
Bertels X, Edris A, Garcia-Aymerich J, Faner R, Meteran H, Sigsgaard T, et al.
BMJ Open Respir Res . 2023 Aug; 10(1). PMID: 37612099
Background: The prevalence and clinical profile of asthma with airflow obstruction (AO) remain uncertain. We aimed to phenotype AO in population- and clinic-based cohorts. Methods: This cross-sectional multicohort study included...
3.
Walters R, Millwood I, Lin K, Schmidt Valle D, McDonnell P, Hacker A, et al.
Cell Genom . 2023 Aug; 3(8):100361. PMID: 37601966
The China Kadoorie Biobank (CKB) is a population-based prospective cohort of >512,000 adults recruited from 2004 to 2008 from 10 geographically diverse regions across China. Detailed data from questionnaires and...
4.
Packer R, Williams A, Hennah W, Eisenberg M, Shrine N, Fawcett K, et al.
Bioinformatics . 2023 Feb; 39(4). PMID: 36744935
Summary: DeepPheWAS is an R package for phenome-wide association studies that creates clinically curated composite phenotypes and integrates quantitative phenotypes from primary care data, longitudinal trajectories of quantitative measures, disease...
5.
Edris A, Callier E, Lahousse L
BMC Med Genomics . 2022 Sep; 15(Suppl 3):193. PMID: 36096833
Background: Personalized medicine is an emerging field, aiming to improve the safety and efficacy of pharmacotherapy. The field's implementation in clinical care is steadily increasing. Pharmacogenomics are one example of...
6.
Wang A, Lahousse L, Dahlin A, Edris A, McGeachie M, Lutz S, et al.
Thorax . 2022 May; 78(5):432-441. PMID: 35501119
Introduction: Older adults have the greatest burden of asthma and poorest outcomes. The pharmacogenetics of inhaled corticosteroid (ICS) treatment response is not well studied in older adults. Methods: A genome-wide...
7.
Edris A, Lahousse L
Minerva Med . 2021 May; 112(5):573-581. PMID: 33988014
Introduction: Novel treatments target eosinophilic inflammation in type 2 asthma. We aimed to evaluate and meta-analyze the efficacy of monoclonal antibodies to reduce exacerbation rate. Evidence Acquisition: PubMed and Embase...
8.
Terzikhan N, Xu H, Edris A, Bracke K, Verhamme F, Stricker B, et al.
ERJ Open Res . 2021 Mar; 7(1). PMID: 33748261
Background: Epigenetics may play an important role in the pathogenesis of lung diseases. However, little is known about the epigenetic factors that influence impaired gas exchange at the lung. Aim:...
9.
Edris A, de Roos E, McGeachie M, Verhamme K, Brusselle G, Tantisira K, et al.
Clin Exp Allergy . 2021 Jan; 52(1):33-45. PMID: 33428814
Background: Inhaled corticosteroids (ICS) are a cornerstone of asthma treatment. However, their efficacy is characterized by wide variability in individual responses. Objective: We investigated the association between genetic variants and...
10.
Edris A, Vanoverschelde A, Bushaj P, Van Nieuwerburgh F, Lahousse L
Pharmacogenomics J . 2020 Aug; 21(1):78-84. PMID: 32848197
Over the past decade, pharmacogenetics (PGx) became an essential tool for personalized medicine although its clinical implementation is still limited. We aimed to assess the current level of knowledge, applications,...