Ahmad Al Khleifat
Overview
Explore the profile of Ahmad Al Khleifat including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
56
Citations
1388
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Iacoangeli A, Dilliott A, Al Khleifat A, Andersen P, Basak N, Cooper-Knock J, et al.
J Neurol Neurosurg Psychiatry
. 2025 Feb;
PMID: 39947885
Background: Despite several studies suggesting a potential oligogenic risk model in amyotrophic lateral sclerosis (ALS), case-control statistical evidence implicating oligogenicity with disease risk or clinical outcomes is limited. Considering its...
2.
Grant O, Iacoangeli A, Zwamborn R, van Rheenen W, Byrne R, van Eijk K, et al.
bioRxiv
. 2024 Dec;
PMID: 39651197
Sex is an important covariate in all genetic and epigenetic research due to its role in the incidence, progression and outcome of many phenotypic characteristics and human diseases. Amyotrophic lateral...
3.
Saez-Atienzar S, Souza C, Chia R, Beal S, Lorenzini I, Huang R, et al.
Cell Genom
. 2024 Oct;
4(11):100679.
PMID: 39437787
Repeat expansions in the C9orf72 gene are the most common genetic cause of (ALS) and frontotemporal dementia (FTD). Like other genetic forms of neurodegeneration, pinpointing the precise mechanism(s) by which...
4.
Shojaie A, Al Khleifat A, Garrahy S, Habash-Bailey H, Thomson R, Opie-Martin S, et al.
Amyotroph Lateral Scler Frontotemporal Degener
. 2024 Sep;
25(7-8):702-707.
PMID: 39218010
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the gradual death of motor neurons in the brain and spinal cord, leading to fatal paralysis. Socioeconomic status (SES) is...
5.
Pain O, Jones A, Al Khleifat A, Agarwal D, Hramyka D, Karoui H, et al.
Heliyon
. 2024 Aug;
10(15):e35342.
PMID: 39170265
Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. This study integrates common genetic association results from the latest ALS genome-wide association study (GWAS) summary statistics with functional genomic...
6.
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS
Marriott H, Spargo T, Al Khleifat A, Andersen P, Basak N, Cooper-Knock J, et al.
Ann Clin Transl Neurol
. 2024 May;
11(7):1775-1786.
PMID: 38775181
Objective: Neurofilament heavy-chain gene (NEFH) variants are associated with multiple neurodegenerative diseases, however, their relationship with ALS has not been robustly explored. Still, NEFH is commonly included in genetic screening...
7.
Harvey C, Weinreich M, Lee J, Shaw A, Ferraiuolo L, Mortiboys H, et al.
Heliyon
. 2024 Feb;
10(3):e24975.
PMID: 38317984
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving selective vulnerability of energy-intensive motor neurons (MNs). It has been unclear whether mitochondrial function is an upstream driver or a...
8.
Ryan M, Doherty M, Al Khleifat A, Costello E, Hengeveld J, Heverin M, et al.
Neurol Genet
. 2023 Dec;
10(1):e200112.
PMID: 38149039
Background And Objectives: A hexanucleotide repeat expansion in the noncoding region of the gene is the most common genetically identifiable cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia in...
9.
Marriott H, Kabiljo R, Hunt G, Al Khleifat A, Jones A, Troakes C, et al.
Acta Neuropathol Commun
. 2023 Dec;
11(1):208.
PMID: 38129934
Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic heterogeneity. Machine learning approaches have previously been utilised for patient stratification in ALS as they can disentangle complex disease landscapes. However,...
10.
Shojaie A, Al Khleifat A, Sarraf P, Al-Chalabi A
Amyotroph Lateral Scler Frontotemporal Degener
. 2023 Nov;
25(3-4):237-241.
PMID: 37981575
Objective: We investigated non-motor symptoms in ALS using sequential questionnaires; here we report the findings of the second questionnaire. Methods: A social media platform (Twitter, now known as X) was...