Agnieszka E Laudy
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Explore the profile of Agnieszka E Laudy including associated specialties, affiliations and a list of published articles.
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22
Citations
188
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Recent Articles
1.
Tyski S, Bocian E, Laudy A
Pol J Microbiol
. 2024 Dec;
73(4):413-431.
PMID: 39618289
Disinfectants and antiseptics lead in reducing the number of microorganisms, including pathogenic ones, thus limiting the number of infections. In the veterinary field, disinfection prevents the transfer of pathogenic microorganisms...
2.
Krajewska J, Tyski S, Laudy A
Pharmaceuticals (Basel)
. 2024 Aug;
17(8).
PMID: 39204172
Despite the urgent need for new antibiotics, very few innovative antibiotics have recently entered clinics or clinical trials. To provide a constant supply of new drug candidates optimized in terms...
3.
Nowicki K, Krajewska J, Stepniewski T, Wielechowska M, Winska P, Kaczmarczyk A, et al.
RSC Med Chem
. 2024 May;
15(5):1751-1772.
PMID: 38784477
Benzosiloxaboroles are an emerging class of medicinal agents possessing promising antimicrobial activity. Herein, the expedient synthesis of two novel thiol-functionalized benzosiloxaboroles 1e and 2e is reported. The presence of the...
4.
Krajewska J, Chyzy P, Durka K, Winska P, Krzysko K, Lulinski S, et al.
Molecules
. 2023 Nov;
28(21).
PMID: 37959781
Over 30 compounds, including -, -, and -phenylenediboronic acids, -substituted phenylboronic acids, benzenetriboronic acids, di- and triboronated thiophenes, and pyridine derivatives were investigated as potential β-lactamase inhibitors. The highest activity...
5.
Sloczynska A, Wand M, Bock L, Tyski S, Laudy A
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298476
The efflux pumps, beside the class D carbapenem-hydrolysing enzymes (CHLDs), are being increasingly investigated as a mechanism of carbapenem resistance in . This study investigates the contribution of efflux mechanism...
6.
Krajewska J, Tyski S, Laudy A
Antimicrob Agents Chemother
. 2023 Apr;
67(5):e0137322.
PMID: 37022162
The analysis of antimicrobial activity is usually MIC- and minimal bactericidal concentration (MBC)-focused, though also crucial are resistance-related parameters, e.g., the frequency of spontaneous mutant selection (FSMS), the mutant prevention...
7.
Zajac O, Tyski S, Laudy A
Biology (Basel)
. 2022 Sep;
11(7).
PMID: 36101423
Levofloxacin is considered an alternative treatment option of infections to trimethoprim/sulfamethoxazole. The fluoroquinolone resistance in is usually caused by an overproduction of efflux pumps. In this study, the contribution of...
8.
Krajewska J, Nowicki K, Durka K, Marek-Urban P, Winska P, Stepniewski T, et al.
RSC Adv
. 2022 Sep;
12(36):23099-23117.
PMID: 36090419
Two isomeric benzosiloxaborole derivatives 3a and 5a bearing fluorine and 4,4-dimethyl-2-oxazolin-2-yl substituents attached to the aromatic rings were obtained. Both compounds were prone to hydrolytic cleavage of the oxazoline ring...
9.
Zajac O, Tyski S, Laudy A
Biology (Basel)
. 2022 Jan;
11(1).
PMID: 35053103
An increase of nosocomial infections caused by strains has recently been observed all over the world. The isolation of these bacteria from the blood is of particular concern. In this...
10.
Sloczynska A, Wand M, Tyski S, Laudy A
Int J Mol Sci
. 2021 Apr;
22(5).
PMID: 33801221
is an important cause of nosocomial infections worldwide. The elucidation of the carbapenem resistance mechanisms of hospital strains is necessary for the effective treatment and prevention of resistance gene transmission....