Agnieszka A Zurek
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Explore the profile of Agnieszka A Zurek including associated specialties, affiliations and a list of published articles.
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12
Citations
521
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Recent Articles
1.
Yu J, Wang D, Bonin R, Penna A, Alavian-Ghavanini A, Zurek A, et al.
EBioMedicine
. 2019 Mar;
42:203-213.
PMID: 30878595
Background: Gabapentin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Its anticonvulsant, analgesic and anxiolytic properties suggest that it increases GABAergic inhibition; however, the molecular basis for...
2.
Sterley T, Baimoukhametova D, Fuzesi T, Zurek A, Daviu N, Rasiah N, et al.
Nat Neurosci
. 2018 Jan;
21(3):393-403.
PMID: 29311741
Stress can trigger enduring changes in neural circuits and synapses. The behavioral and hormonal consequences of stress can also be transmitted to others, but whether this transmitted stress has similar...
3.
Perez-Sanchez J, Lorenzo L, Lecker I, Zurek A, Labrakakis C, Bridgwater E, et al.
J Neurosci Res
. 2016 Oct;
95(6):1307-1318.
PMID: 27792253
Neuronal inhibition mediated by GABA receptors constrains nociceptive processing in the spinal cord, and loss of GABAergic inhibition can produce allodynia and hyperalgesia. Extrasynaptic α5 subunit-containing GABA receptors (α5GABA Rs)...
4.
Zurek A, Kemp S, Aga Z, Walker S, Milenkovic M, Ramsey A, et al.
Ann Clin Transl Neurol
. 2016 May;
3(5):392-8.
PMID: 27231709
The prevalence of autism spectrum disorders (ASDs), which affect over 1% of the population, has increased twofold in recent years. Reduced expression of GABAA receptors has been observed in postmortem...
5.
Zurek A, Yu J, Wang D, Haffey S, Bridgwater E, Penna A, et al.
J Clin Invest
. 2014 Nov;
124(12):5437-41.
PMID: 25365226
Many patients who undergo general anesthesia and surgery experience cognitive dysfunction, particularly memory deficits that can persist for days to months. The mechanisms underlying this postoperative cognitive dysfunction in the...
6.
Diaz M, Vollmer C, Zamudio-Bulcock P, Vollmer W, Blomquist S, Morton R, et al.
Neuropharmacology
. 2013 Dec;
79:262-74.
PMID: 24316160
Exposure to ethanol (EtOH) during fetal development can lead to long-lasting alterations, including deficits in fine motor skills and motor learning. Studies suggest that these are, in part, a consequence...
7.
Bonin R, Zurek A, Yu J, Bayliss D, Orser B
PLoS One
. 2013 Mar;
8(3):e58679.
PMID: 23516534
Changes in the expression of γ-aminobutyric acid type A (GABAA) receptors can either drive or mediate homeostatic alterations in neuronal excitability. A homeostatic relationship between α5 subunit-containing GABAA (α5GABAA) receptors...
8.
Wang D, Zurek A, Lecker I, Yu J, Abramian A, Avramescu S, et al.
Cell Rep
. 2012 Sep;
2(3):488-96.
PMID: 22999935
Systemic inflammation causes learning and memory deficits through mechanisms that remain poorly understood. Here, we studied the pathogenesis of memory loss associated with inflammation and found that we could reverse...
9.
Zurek A, Bridgwater E, Orser B
Anesth Analg
. 2012 Mar;
114(4):845-55.
PMID: 22383672
Background: General anesthetics cause cognitive deficits that persist much longer than would be expected on the basis of their pharmacokinetics. The cellular mechanisms underlying these postanesthetic cognitive deficits remain unknown....
10.
Martin L, Zurek A, Bonin R, Oh G, Kim J, Mount H, et al.
Behav Brain Res
. 2010 Nov;
217(2):379-85.
PMID: 21070817
The precise mechanisms underlying the memory-blocking properties of ethanol are unknown, in part because ethanol targets a wide array of neurotransmitter receptors and transporters. The aim of this study was...