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Agnete Brunsvik Fredriksen

Explore the profile of Agnete Brunsvik Fredriksen including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Kuczkowska K, Bjerkan L, Stubsrud E, Husbyn H, Chellappa S, Hauge A, et al.
Sci Rep . 2023 Nov; 13(1):18902. PMID: 37919366
Throughout the COVID-19 pandemic, several variants of concern (VoC) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have evolved, affecting the efficacy of the approved COVID-19 vaccines. To address...
2.
Grodeland G, Fredriksen A, Loset G, Vikse E, Fugger L, Bogen B
J Immunol . 2016 Sep; 197(9):3575-3585. PMID: 27671110
It has been difficult to translate promising results from DNA vaccination in mice to larger animals and humans. Previously, DNA vaccines encoding proteins that target Ag to MHC class II...
3.
Lambert L, Kinnear E, McDonald J, Grodeland G, Bogen B, Stubsrud E, et al.
Front Immunol . 2016 Sep; 7:321. PMID: 27602032
Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza...
4.
Grodeland G, Mjaaland S, Roux K, Fredriksen A, Bogen B
J Immunol . 2013 Aug; 191(6):3221-31. PMID: 23956431
New influenza A viruses with pandemic potential periodically emerge due to viral genomic reassortment. In the face of pandemic threats, production of conventional egg-based vaccines is time consuming and of...
5.
Froyland M, Ruffini P, Thompson K, Gedde-Dahl T, Fredriksen A, Bogen B
Eur J Haematol . 2011 Feb; 86(5):385-95. PMID: 21332794
Objectives:   A homodimeric fusion DNA vaccine targeting idiotype (Id) to antigen-presenting cells (APC) induced robust tumor protection in a mouse model of multiple myeloma (MM). Similar Id vaccine molecules were...
6.
Fredriksen A, Bogen B
Blood . 2007 Jun; 110(6):1797-805. PMID: 17540847
V regions of monoclonal Ig express an exquisite B-cell tumor-specific antigen called idiotype (Id). Id is a weak antigen and it is important to improve immunogenicity of Id vaccines. Chemokine...
7.
Schjetne K, Thommesen J, Fredriksen A, Lunde E, Sandlie I, Bogen B
Eur J Immunol . 2005 Sep; 35(11):3142-52. PMID: 16184515
In order to prevent or ameliorate autoimmune disease, it would be desirable to induce central tolerance to peripheral self-antigens. We have investigated whether recombinant antibodies (Ab) that deliver T cell...
8.
Holmoy T, Fredriksen A, Thompson K, Hestvik A, Bogen B, Vartdal F
Eur J Immunol . 2005 May; 35(6):1786-94. PMID: 15864781
Due to somatic recombination and hypermutation, Ig variable heavy (V(H)) and light (V(L)) regions contain unique immunogenic determinants, idiotopes (Id), which can stimulate T cells. To address the relevance of...